Since ancient times, the essential oils (EOs) of many aromatic plants have been used as bioactive ingredients in drug, food and cosmetic formulations all over the world. Significant biological properties have also been attributed to Hypericum EOs. Hypericum is a genus of about 450 species in the Guttiferae family, formerly often treated separately in their own Hypericaceae family. Despite the l...

Herb-drug interactions are an important safety concern and this study was conducted regarding the interaction between the natural top-selling antidepressant remedy Hypericum perforatum (Hypericaceae) and conventional drugs. This study examined the influence of acute pretreatment with different extracts of Hypericum perforatum from Serbia on pentobarbital-induced sleeping time, impairment of mot...

background & aim: vast variety of plants in various regions of the country and lack of enough information on their chemical combinations, sometimes lead to triggering poisoning and unsatisfied complications. regarding to fabulous herbal characteristics of hypricum, many research about poisoning and side effects of high concentrations of h. scabrum have not taken place until now. therefore r...

Among the widespread plant species in Azerbaijan, genus Hypericum L. which dates back to Cenozoic era and belongs family Hypericaceae takes special place. 80% of total number belonging are concentrated Hypericum, is distinguished by its many-sided areas application, especially pharmaceutical, decorative dye industries. This considered one largest genera flowering plants terms diversity (22%). A...

Quercetin 7-rhamnoside (Q7R) is one of the main flavonoid components of Hypericum japonicum. However, whether Q7R is one of the active ingredients responsible for the hepatopreventive effects of Hypericum japonicum has not yet been ascertained. Thus, the aim of the present study was to elucidate whether Q7R attenuates apoptosis induced by glycochenodeoxycholic acid (GCDC) in vitro, and to eluci...