A framework is formulated for the development of a predictive structure-activity relationship for the temperature-dependent rate coefficients of H-migration in substituted alkoxy radicals. It is based on a multi-conformer transition state theory model, using quantum chemical characterizations of alkoxy radicals and their transition states for isomerisation. Using this framework, a SAR is then d...

In the mol-ecule of the title compound, C(7)H(8)O(2), the phenol O and hydroxy-methyl C atoms lie in the ring plane [deviations of -0.015 (3) and and 0.013 (3) Å, respectively]. In the crystal structure, inter-molecular O-H⋯O hydrogen bonds link mol-ecules into a network. A weak C-H⋯π inter-action is also found.

The title compound, C23H24N4OS, contains a highly asymmetric bifurcated intramolecular hydrogen bond between the hydroxy group and two pyrazole N atoms. The compound associates into centrosymmetric dimers in the crystal through two unique C-H...pi interactions, which are in turn linked into a (6,3)-network through an additional intermolecular C-H...N hydrogen bond.

Novel glycosidic compounds, 4,6-dialkoxy-1,3,5-triazin-2-yl β-lactosides (DAT-β-Lac), have been prepared directly in water from lactose. The reaction was carried out on a laboratory scale without protecting the hydroxy groups of lactose. The resulting triazine derivatives were found to be recognized by endo-β1,4-glucanase III from Trichoderma reesei (EGIII). The EGIII-catalysed transglycosylati...

Thiobenzanilides substituted in thioacyl moiety with one or more hydroxy groups are interesting for their biological effects depending on the substitution pattern. New findings in mechanisms of action of 2-hydroxybenzanilides insert 2-hydroxybenzanilides and their analogues, e.g. substituted thiobenzanilides, among interesting compounds in the development of new potential antimicrobial drugs. T...

In the title compound, C(25)H(23)N(3)O(3), the seven-membered diazepine ring adopts a boat conformation with the hydroxy-substituted C atom at the prow and fused-ring C atoms at the stern. The crystal packing features C-H⋯O, C-H⋯π and N-H ⋯π inter-actions.

The Pioneering Process: DR. ISAIAH BOWMAN ............ 521 a Possible Source of Inhibitor for Tumors: DR. JAMES B. MURPHY and ERNEST STURM. MetaScientific Events: amino Para-hydroxy Phenyl Arsine Oxide as an The Zoological Society of London; Research ComAntisyphilitic Agent: DR. ARTHUR L. TATUM and mittees on the Section of Hydrology of the AmerGARRETT A. COOPER. Airplane Oiling to Control ican...

Compounds formed by exchanging one of the resveratrol hydroxy groups to methoxy or formyl groups are biologically important. Quantum chemical DFT calculations were applied for the simulation of some of their properties. Their optimized structures and charge distributions were computed. Based on the calculated vibrational force constants and optimized molecular structure infrared and Raman spect...