نتایج جستجو برای: hydrophilic gnps

تعداد نتایج: 16088  

Journal: :Histology and histopathology 2017
Haseeb A Khan Khalid E Ibrahim Ayaat Khan Salman H Alrokayan Abdullah S Alhomida

Recently, gold nanoparticles (GNPs) have shown promising applications in targeted drug delivery and contrast imaging. Although in vitro cytotoxicity of GNPs has been thoroughly studied, there are limited data on in vivo toxicity of GNPs. In this study, we evaluated the effects of intraperitoneally injected 10 nm and 50 nm GNPs (5 μg/animal) on the expression of proinflammatory cytokines (IL-1β,...

2016
Baomin Wang Ruishuang Jiang Zhenlin Wu

In this work, graphene nanoplatelets (GNPs) were dispersed uniformly in aqueous solution using methylcellulose (MC) as a dispersing agent via ultrasonic processing. Homogenous GNP suspensions were incorporated into the cement matrix to investigate the effect of GNPs on the mechanical behavior of cement paste. The optimum concentration ratio of GNPs to MC was confirmed as 1:7 by ultraviolet visi...

Journal: :Nanotechnology 2014
Chia-Hui Lee Shih-Han Syu Yu-Shiun Chen Saber M Hussain Andrei Aleksandrovich Onischuk Wen Liang Chen G Steven Huang

Nanoparticles are potential threats to human health and the environment; however, their medical applications as drug carriers targeting cancer cells bring hope to contemporary cancer therapy. As a model drug carrier, gold nanoparticles (GNPs) have been investigated extensively for in vivo toxicity. The effect of GNPs on the immune system, however, has rarely been examined. Antibody-secreting ce...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه گیلان - دانشکده علوم پایه 1392

امروزه الکترودهای اصلاح شده با نانوذرات به عنوان جایگزینی در آنالیز الکتروشیمیایی ترکیبات آلی و معدنی مطرح شده است. نانوفلزات حداقل سه عملکرد مهم در آنالیز الکتروشیمیایی ظاهر می کنند که عبارتند از: زبر نمودن سطح مشترک رسانای حسگر، عملکردهای کاتالیتیکی و ویژگی رسانایی. در این مطالعه، از نانوذرات طلا (gnps) به عنوان نانوذرات فلزی اصلاح کننده در الکترود خمیر کربنی (cpe) استفاده شده است. به دلیل وی...

2016
Tingting Liu Ping Wu Chengde Gao Pei Feng Tao Xiao Youwen Deng Cijun Shuai Shuping Peng

A synergetic effect between carbon nanotubes (CNTs) and graphene on diopside (Di) scaffolds was demonstrated. 3D network architecture in the matrix was formed through the 1D CNTs inlaid among the 2D graphene platelets (GNPs). The mechanical properties of the CNTs/GNPs/Di scaffolds were significantly improved compared with the CNTs/Di scaffolds and GNPs/Di scaffolds. In addition, the scaffolds e...

2016
Hossein Khosravi Bijan Hashemi Faezeh Rahmani Ahmad Ebadi

PURPOSE In this work, gold nanoparticles (GNPs) were embedded in the MAGIC-f polymer gel irradiated with the 192Ir brachytherapy sources. MATERIAL AND METHODS At the first plexiglas phantom was made as the human pelvis. The GNPs were synthesized with 15 nm in diameter and 0.1 mM (0.0197 mg/ml) in concentration by using a chemical reduction method. Then, the MAGIC-f gel was synthesized. The fa...

Journal: :Nanomedicine : nanotechnology, biology, and medicine 2011
Ajay Sharma Ashish Tandon Jonathan C K Tovey Rangan Gupta J David Robertson Jennifer A Fortune Alexander M Klibanov John W Cowden Frank G Rieger Rajiv R Mohan

UNLABELLED This study examined the gene transfer efficiency and toxicity of 2-kDa polyethylenimine conjugated to gold nanoparticles (PEI2-GNPs) in the human cornea in vitro and rabbit cornea in vivo. PEI2-GNPs with nitrogen-to-phosphorus ratios of up to 180 exhibited significant transgene delivery in the human cornea without altering the viability or phenotype of these cells. Similarly, PEI2-GN...

2008
Liping Sun Zhaowu Zhang Shuang Wang Jianfeng Zhang Hui Li Lei Ren Jian Weng Qiqing Zhang

Gold nanoparticles (GNPs) are widely used to detect DNA. We studied the effect of pH on the assembly/disassembly of single-stranded DNA functionalized GNPs. Based on the different binding affinities of DNA to GNPs, we present a simple and fast way that uses HCl to drive the assembly of GNPs for detection of DNA sequences with single nucleotide differences. The assembly is reversible and can be ...

2015
Jenny Domey Ulf Teichgräber Ingrid Hilger

Due to their high X-ray attenuation, gold nanoparticles (GNPs) emerged as preclinical contrast agents by giving high vasculature contrast. For this reason, GNPs are regularly applied for computed tomography (CT) imaging of tumors but not for the visualization of inflammation. The aim of this study was to evaluate the biocompatibility and applicability of preclinical GNPs (AuroVist™) of two diff...

Journal: :Bioorganic & medicinal chemistry letters 2014
Yunlong Pan Qing Wu Ruiying Liu Mingtao Shao Jiang Pi Xiaoxu Zhao Li Qin

Tumor angiogenesis is a complicated process based upon a sequence of interactions between tumor and vessel endothelial cells. Tumor conditioned medium has been widely used to stimulate endothelial cells in vitro angiogenesis. This work was aimed to investigate the effects of gold nanoparticles (GNPs) on angiogenesis in hepatic carcinoma-conditioned endothelial cells. Human umbilical vein endoth...

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