نتایج جستجو برای: hydrodynamic based gene delivery
تعداد نتایج: 4067033 فیلتر نتایج به سال:
50 kDa chitosan was conjugated with folate, a specific tissue-targeting ligand. Nanoparticles such as chitosan-DNA and folate-chitosan-DNA were prepared by coacervation process. The hydrodynamic intravenous injection of nanoparticles was performed in the right posterior paw in normal and arthritic rats. Our results demonstrated that the fluorescence intensity of DsRed detected was 5 to 12 times...
Preparation and characterization of friendly colloidal Hydroxyapatite based on natural Milk’s casein
Biocompatible hydroxyapatite nanocomposites are biocompatible, biodegradable and nontoxic have been paid many attentions as one of the most suitable vehicle for drug delivery use. Our objective in this work was to prepare and characterize caseins based HA nanocomposite in a colloidal form for drug delivery purposes. Casein biopolymer was firstly extracted from skimmed milk by adding acetic acid...
Preparation and characterization of friendly colloidal Hydroxyapatite based on natural Milk’s casein
Biocompatible hydroxyapatite nanocomposites are biocompatible, biodegradable and nontoxic have been paid many attentions as one of the most suitable vehicle for drug delivery use. Our objective in this work was to prepare and characterize caseins based HA nanocomposite in a colloidal form for drug delivery purposes. Casein biopolymer was firstly extracted from skimmed milk by adding acetic acid...
Cationic polymers are desirable gene carriers because of their better safety profiles than viral delivery systems. Low molecular weight (MW) polymers are particularly attractive, since they display little cytotoxicity, but they are also ineffective for gene delivery. To create effective carriers from low MW polymers palmitic acid (PA) was substituted on 0.6-2.0 kDa polyethylenimines (PEIs) and ...
Liver fibrosis is the final stage of liver diseases that lead to liver failure and cancer. While various diagnostic methods, including the use of serum marker, have been established, no standard therapy has been developed. The objective of this study was to assess the approach of overexpressing matrix metalloproteinase-13 gene (MMP13) in rat liver to prevent liver fibrosis progression. A rat li...
Time-resolved imaging, fluorescence microscopy, and hydrodynamic modeling were used to examine cell lysis and molecular delivery produced by picosecond and nanosecond pulsed laser microbeam irradiation in adherent cell cultures. Pulsed laser microbeam radiation at λ = 532 nm was delivered to confluent monolayers of PtK2 cells via a 40×, 0.8 NA microscope objective. Using laser microbeam pulse d...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید