Dehydration of hydrates of pharmaceutical inactive/active ingredients (pharmaceutical hydrates) may easily occur during storage or manufacturing. Loss of water may have little effect on the crystal lattice, produce less hydrated forms or possibly amorphous form. Characterizing the effects of water loss on crystal hydrate forms is important for understanding the behavior of hydrates throughout t...

[1] We have reviewed the available scientific literature on how natural sources and the atmospheric fate of methane may be affected by future climate change. We discuss how processes governing methane wetland emissions, permafrost thawing, and destabilization of marine hydrates may affect the climate system. It is likely that methane wetland emissions will increase over the next century. Uncert...

Naturally occurring gas hydrates are regarded as an important future source of energy and considerable efforts are currently being invested to develop methods for an economically viable recovery of this resource. The recovery of natural gas from gas hydrate deposits has been studied by a number of researchers. Depressurization of the reservoir is seen as a favorable method because of its relati...

The effect of the concentration of kinetic hydrate inhibitors, polyvinylpyrrolidone (PVP), and polyvinylcaprolactam (PVCap) on the onset and growth of synthetic natural gas hydrates is investigated by measuring the hydrate onset time and gas consumption rate. Although the hydrate onset time is extended by increasing the concentration from 0.5 to 3.0 wt % for both PVP and PVCap, the growth rate ...

Clathrate hydrates are typically stabilized by suitably sized hydrophobic guest molecules. However, it has been experimentally reported that isomers of amyl-alcohol C5H11OH can be enclosed into the 5(12)6(4) cages in structure II (sII) clathrate hydrates, even though the effective radii of the molecules are larger than the van der Waals radii of the cages. To reveal the mechanism of the anomalo...

Gas hydrates were first discovered by Sir HumphryDavy in 1810 [1]. Clathratehydrates are crystalline compounds, formed by the smaller molecules (guest), entrapped within the cavities of a rigid “cage-like” lattice of water molecules (host) at low temperature (typically less than 300K) and high pressure (typically more than 0.6MPa) conditions [2]. The small molecules of gasses, such as methane (...

The examination of ambient thermodynamic conditions suggests that clathrate hydrates could exist in the Martian permafrost, on the surface and in the interior of Titan, as well as in other icy satellites. Clathrate hydrates are probably formed in a significant fraction of planetesimals in the solar system. Thus, these crystalline solids may have been accreted in comets, in the forming giant pla...

Blockage of pipelines by formation and accumulation of clathrate hydrates of natural gases (also called gas hydrates) can compromise project safety and economics in oil and gas operations, particularly at high pressures and low temperatures such as those found in subsea or arctic environments. Cyclopentane (CyC5) hydrate has attracted interest as a model system for studying natural gas hydrates...