b a c k g r o u n d & aim: today, one of the leading causes of pathogenicity and mortality in patients undergoing hemodialysis is their failure to follow the treatment plan. the present research was con- ducted to compare effects of patient-centered  education with family-centered  education on adher- ence with the treatment program. methods & materials: this clinical trial was performed betwee...

Cancer immunotherapy with dendritic cell-tumor cell fusion hybrids induces polyclonal stimulation against a variety of tumor antigens, including unknown antigens. Hybrid cells can prime CTLs, which subsequently develop antitumor responses. The aim of this study was to enhance the known antitumor effect of hybrid vaccination (HC-Vacc) and hybrid-primed adoptive T-cell therapy (HC-ACT) using the ...

In an era when molecular and targeted anticancer therapeutics is a major focus and when understanding drug dynamics in tumor is critical, it seems advantageous to be able to relate drug concentrations in tumors to corresponding biological end points. To that end, a novel method, based on physiologically based hybrid pharmacokinetic models, is presented to predict human tumor drug concentrations...

  Background: Epidemiological changes leading to chronic diseases are becoming more important day by day. Hypertension is also known as a chronic disease. Worldwide prevalence of hypertension have caused serious complications. The disease has become a health problem in all communities. This research aims at analyze the correlation between compliance with the treatment regimen and health locus o...

background: the role and proper dose of pralidoxime in the treatment of organophosphorus (op) compounds poisoning is an unresolved issue .this study was designed to compare the regimen recommended by the world health organization (who) with the commonly used standard regimen of pralidoxime. methods: this was a randomized open labeled prospective study on op poisoned patients admitted to jss hos...

Objective: This study examines the effect of the addition of IMOD, a novel multi-herbal drug to the highly active anti-retroviral therapy (HAART) regimen, on the immunological status of HIV-positive patients. Materials and Methods: A randomized two-parallel-group (HAART group versus HAART+IMOD group), pretest-posttest design was used.Sixty patients with indications for treatment with the HAART ...