Inflammation and immunity may be associated with endothelial cell (EC) injury and thrombus formation. We explored the mechanisms through which a humoral immune response directed against the endothelium might promote coagulation. Using the interaction of anti-EC antibodies and complement (C) with cultured EC as a model, we studied the expression and function of tissue factor, a cofactor for fact...

Atherosclerotic cardiovascular disease is the number one cause of death for adults in Western society. Plasminogen activator inhibitor-1 (PAI-1), the major physiological inhibitor of plasminogen activators, has been implicated in both thrombogenesis and atherogenesis. Previous studies demonstrated that copper-oxidized low-density lipoprotein (C-oLDL) stimulated production of PAI-1 in vascular e...

BACKGROUND Retroperitoneal lymph node (RLN) metastasis is an important indicator of endometrial cancer (EC) prognosis. Because vascular endothelial growth factor c (VEGF-c) is known to influence lymphangiogenesis and thereby lymph node metastasis, this study assessed the relationship of VEGF-c mRNA expression with RLN metastasis in EC. METHODS The uterine muscularis mucosae of New Zealand whi...

In this study we present the original formulation of a deep eutectic mixture based on lithium imide salt as an electrolyte for Li-ion batteries. The non-flammable liquid obtained by mixing asymmetric (fluorosulfonyl) (trifluoromethanesulfonyl) (LiFTFSI) with ethylene carbonate (EC) demonstrates its applicability safer By comparison conventional electrolytes containing same salt, in 3EC/7EMC and...

While the effect of soil temperature and moisture on soil CO2 efflux (Ec) has been widely investigated, the relationship between Ec and soil carbon (C), root, and stand parameters has not been comprehensively examined or quantified across extensive spatial and temporal scales. We measured Ec in loblolly pine (Pinus taeda L.) stands located on the South Carolina Coastal Plain across sites, seaso...

Protooncogenes expressed in murine embryonal carcinoma (EC) cells or their differentiated daughter cells include more or less ubiquitously expressed protooncogenes such as c-myc, c-K-ras, and c-abl, as well as c-onc genes with a very restricted expression pattern. Examples of the latter are N-myc, c-mos, and int-2. These c-onc genes are transcriptionally active in EC cells, as well as in germ c...

Foodborne pathogens continue to pose a potential food safety hazard in ready-to-eat (RTE) meat. Chlorine is commonly used to sanitize processing equipment where Escherichia coli O157:H7 (Ec) may survive and contaminate food products. The objective of this study was to characterize the survival behavior of Ec with different stresses on RTE meats. A multi-strain cocktail of Ec was pre-treated wit...

Bio-char with rich pore structure was obtained by pyrolysis of enteromorpha clathrate (EC) and subsequent activation process. The effect methods, KOH concentrations used in heating rate studied. A new method that combined into one step proposed. bio-char via slow at 450°C 700°C had a certain structure. fast almost no effective large amount organic matters still exist the bio-char, while it larg...

To study Ca(2+) signaling in the endothelium of murine feed arteries, we determined the in vitro stability of endothelial cell (EC) tubes freshly isolated from abdominal muscle feed arteries of male and female C57BL/6 mice (5-9 mo, 25-35 g). We tested the hypothesis that intracellular Ca(2+) concentration ([Ca(2+)](i)) responses to muscarinic receptor activation would increase with temperature....

Vascular endothelial cell (EC) barrier integrity is critical to vessel homeostasis whereas barrier dysfunction is a key feature of inflammatory disorders and tumor angiogenesis. We previously reported that hepatocyte growth factor (HGF)-mediated increases in EC barrier integrity are signaled through a dynamic complex present in lipid rafts involving its receptor, c-Met. We extended these observ...