Human leukocyte antigen (HLA)-Cw*0740 differs from HLA-Cw*070101 by one nucleotide substitution at codon 73 (GCT>ACT).

The literature review presents the characteristics of human leukocyte antigen (HLA)-B27 as a factor contributing to development psoriatic arthritis. HLA-B27 is class I surface encoded by major histocompatibility complex (MHC) B locus located on chromosome 6. main function present antigenic peptides CD8+ T-cells. most important genetic biomarker for arthritis, it provides phenotypic differentiat...

Immunosurveillance is an extrinsic mechanism of cancer suppression that eliminates nascent tumors. However, the selection imposed by immunosurveillance can drive tumor evolution and the emergence of clinically apparent neoplasms. Mechanisms of immune escape acquired by less immunogenic variants during this process, termed immunoediting, may contribute significantly to malignant progression. In ...

Human leukocyte antigen (HLA) gene region encodes a set of HLA molecules functioning critical roles in immune response. Each HLA gene locus shows extensive polymorphism with ever-increasing number of alleles. The HLA nomenclature system for alleles defined by DNA typing was first established in 1987 and has been revised several times. Recently, it has been revised again with a new frame that ca...

33 The Olive Baboon (Papio anubis): A Potential Animal Model to Study the Function of Human Leukocyte Antigen-G (HLA-G) Langat, D.K. (Kansas City, Kans./Nairobi); Morales, P.J. (Kansas City, Kans.); Fazleabas, A.T. (Chicago, Ill.); Mwenda, J.M. (Nairobi); Hunt, J.S. (Kansas City, Kans.) 36 The Prevalence of Anti-Phospholipid Antibodies in a Selected Population of Kenyan Women and Development of...

Human leukocyte antigen-G which is an immune tolerance effecter molecule has an important role in the maintenance of fetus during pregnancy. Abortion is one of the complications of pregnancy period.  In this research, we have studied levels of HLA-G 5, HLA-G7 isoforms in the abortion-threatened pregnant women in comparison with controls. In a case-control study, 101 abortion-threatened women an...

As one of the non-classical major histocompatibility complex(MHC)-1 antigens, Human Leukocyte Antigen G (HLA-G), has been suggested as a prognostic marker to identify the embryo developmental potential. In the present study, we investigated the potential roles of HLA-G in human spermatogenesis and early embryonic development. Quantitative real-time PCR analysis revealed that HLA-G's expression ...

33 The Olive Baboon (Papio anubis): A Potential Animal Model to Study the Function of Human Leukocyte Antigen-G (HLA-G) Langat, D.K. (Kansas City, Kans./Nairobi); Morales, P.J. (Kansas City, Kans.); Fazleabas, A.T. (Chicago, Ill.); Mwenda, J.M. (Nairobi); Hunt, J.S. (Kansas City, Kans.) 36 The Prevalence of Anti-Phospholipid Antibodies in a Selected Population of Kenyan Women and Development of...

  Background and Objective: The outcome of hepatitis B virus (HBV) infection may be influenced by host factors like Human Leukocyte Antigen (HLA). We have investigated HLA-A and DRB1 alleles in patients with persistent hepatitis B infection compared to subjects who had spontaneously recovered from HBV infection. To complete the findings of this study we performed another survey in certain HLA ...