RATIONALE The nitrated sugar alcohols mannitol hexanitrate (MHN), sorbitol hexanitrate (SHN) and xylitol pentanitrate (XPN) are in the same class of compounds as the powerful military-grade explosive pentaerythritol tetranitrate (PETN) and the homemade explosive erythritol tetranitrate (ETN) but, unlike for PETN and ETN, ways to detect MHN, SHN and XPN by mass spectrometry (MS) have not been fu...

Current development in catalyst discovery includes combinatorial synthesis methods for the rapid generation of compound libraries combined with high-throughput performance-screening methods to determine the associated activities. Of these novel methodologies, mass spectrometry (MS) based flow chemistry methods are especially attractive due to the ability to combine sensitive detection of the fo...

Astaxanthin, a powerful antioxidant, is a good candidate for the prevention of intracellular oxidative stress. The aim of the study was to compare the antioxidant activity of astaxanthin present in two natural extracts from Haematococcus pluvialis, a microalgae strain, with that of synthetic astaxanthin. Natural extracts were obtained either by solvent or supercritical extraction methods. UV, H...

from Pollen of Hippeastrum x hortorum Nikolay Youhnovski, Christa Werner* and Manfred Hesse Organisch-chemisches Institut der Universität Zürich. Winterthurerstrasse 190, CH-8057 Zürich. Fax: +41-1-6356812. E-mail: [email protected] * Author of correspondance and reprint requests Z. Naturforsch. 56c, 526-530 (2001); received March 27, 2001 Amaryllidaceae. Anthers, Hydroxycinnamoyl polyamines...

Fusarium fungi are widely found in agricultural products, worldwide and can produce a great variety of mycotoxins. Fumonisins, produced by F. moniliforme, and deoxynivalenol, produced by F. graminearum, are two such mycotoxins that have received considerable attention as food safety concerns by regulatory agencies. High Performance Liquid Chromatography/Mass Spectrometry (HPLC/MS) was found to ...

We present the development and characterization of a combination of a micro-orifice volatilization impactor (MOVI) and an ion trap mass spectrometer (IT/MS) with an atmospheric-pressure chemical ionization (APCI) source. The MOVI is a multi-jet impactor with 100 nozzles, allowing the collection of aerosol particles by inertial impaction on a deposition plate. The pressure drop behind the nozzle...

Pyrolysis oil from the slow pyrolysis of German brown coal from Schöningen, obtained at a temperature of 500°C, was separated and analyzed using hyphenation of gas chromatography with an atmospheric pressure chemical ionization source operated in negative ion mode and Fourier transform ion cyclotron resonance mass spectrometry (GC-APCI-FT-ICR-MS). Development of this ultrahigh-resolving analysi...

Profiles of the urinary metabolites of 2,4-toluenediisocyanate (2,4-TDI) and 2,4toluenediamine (2,4-TDA) have been studied in rats with the aim to find suitable biomarkers of 2,4-TDI exposure. The animals were dosed intraperitoneally with 0.10 mmol/kg of each compound. Urine was cleaned-up by the extraction with acetonitrile and by preparative HPLC to remove polar matrix components. The residuu...