Crystalline surface layer proteins (S-layer proteins) have considerable potential for the crystalline arrays in biotechnology, biomimetics and nonlife applications, including areas such as microelectronics and molecular nanotechnology. The extensive application potential of surface layers in nanobiotechnology is according to the particular inherent attributes of the single molecular arrays cons...

We examined 12 pairs of strains of Escherichia coli and Klebsiella pneumoniae isolated from mixed infections in human for the presence of the Yersinia high-pathogenicity island (HPI). In one case both isolates carried the HPI, whereas in 11 cases one strain of the pair was HPI-positive. Although there were di$erences in the organization of the Yersinia HPI, all HPI-positive isolates were able t...

The high-pathogenicity island (HPI) of yersiniae encodes an iron uptake system represented by its siderophore yersiniabactin (Ybt). The HPI is present in yersiniae with high levels of pathogenicity--i.e., Yersinia pestis, Y. pseudotuberculosis, and Y. enterocolitica biogroup (BG) 1B--but absent in Y. enterocolitica strains with low (BG 2 to 5) and no (BG 1A) levels of pathogenicity and has been...

Research on natural products containing hexahydropyrrolo[2,3-b]indole (HPI) has dramatically increased during the past few years. Newly discovered natural products with complex structures and important biological activities have recently been isolated and synthesized. This review summarizes the structures, biological activities, and synthetic routes for natural compounds containing HPI, emphasi...

The vertical dimensions of the well-characterized test samples tobacco mosaic virus, T4 bacteriophage polyhead, purple membrane, and hexagonally packed intermediate (HPI) layer were investigated by tapping mode scanning force microscopy (SFM) in solution. Purple membrane and HPI layer were imaged in both contact mode and tapping mode SFM for direct comparison. All vertical dimensions match the ...

The coronavirus disease 2019 (COVID-19) pandemic has claimed many lives since it was first reported in late December 2019. However, there is still no drug proven to be effective against the virus. In this study, a candidate host–pathogen–interactive (HPI) genome-wide genetic and epigenetic network (HPI-GWGEN) constructed via big data mining. reverse engineering method applied investigate pathog...

Following experimental inoculation of 3-week-old turkeys with different titres (106, 104, 103, 102 and 101 egg infectious dose (EID50)) of A/ostrich/Italy/984/2000 H7N1 highly pathogenic avian influenza virus (HPAIV), the selected tissues and organs were examined for pathological changes. Tissue samples from different organs that obtained from dead and sacrificed birds were fixed in 10% neutral...

The objective of this present study was to describe the clinical-radiological and lung function characteristics of hypersensitivity pneumonitis due to exposure to isocyanates (HPI). Included for study were all those patients diagnosed with HPI (n = 5) from 1995-2010. In all cases, chest CT and complete lung function studies were done. The diagnosis was made with positive specific bronchial prov...

2 Telephone (781) 981-2920; Fax (781) 981-7271; e-mail [email protected] Abstract In this paper, two examples of sensor fusion are demonstrated. The first is hyperspectral imaging (HSI) with Synthetic Aperture Radar (SAR) and the other is HSI with high-resolution panchromatic imaging (HPI). HSI and SAR fusion exploits different phenomenologies from distinctly different sensors. HSI and HPI fu...