A spectral/hp element methodology is utilised to investigate the SAE Notchback geometry with 20∘ backlight and 3∘ diffuser at Re=2.3×106. The study presented here considered two different mesh approaches: one focusing on classical h-type refinement standard solution polynomial order (HFP3) a second case considering relatively coarse combined high (HCP5). For same targeted number of degrees free...

HP 749 (besipirdine; Hoechst-Roussel Pharmaceuticals, Inc., Somerville, NJ) and related analogs belonging to the N-(4-pyridinyl)-1H-indol-1-amine class of compounds have shown a potential to mitigate multiple biochemical deficits associated with Alzheimer's disease. HP 749 has demonstrated cholinergic and nonadrenergic activities both in vitro and in vivo, and has potential for the symptomatic ...

We introduce the notion of a cosheaf on a fan Σ and define the Z2 Hodge spaces Hpq(Σ), which are the homology groups Hp(∧E ) of the qth exterior power of the cosheaf E on Σ. Geometrically, for σ ∈ Σ the stalk Eσ of the cosheaf E is the compact real torus in the real orbit Oσ(R) of the real toric variety XΣ(R). The Z2 Hodge spaces Hpq(Σ) are indexed by pairs p, q with 0 ≤ q ≤ p ≤ d, where d = di...

A periodic breathing (PB) pattern is often observed in chronic heart failure (CHF) patients (pts). In order to clarify the role of this abnormal respiratory activity upon heart period variability we investigated, in a group of 20 stable CHF pts (NYHA class II to III, median EF 24%) showing a PB pattern, 1) whether observed data were consistent with the instability hypothesis of PB and 2) the re...

Muscle sympathetic nerve activity (MSNA) variability is traditionally computed through a low-pass filtering procedure that requires normalization. We proposed a new beat-to-beat MSNA variability computation that preserves dimensionality typical of an integrated neural discharge (i.e., bursts per unit of time). The calibrated MSNA (cMSNA) variability technique is contrasted with the traditional ...

The objective of this work is to develop an algorithm for pansharpening of very high resolution (VHR) satellite imagery that reduces the spectral distortion of the pansharpened images and enhances their spatial clarity with minimal computational costs. In order to minimize the spectral distortion and computational costs, the global injection gain is transformed to the local injection gains usin...

Emerging commercial and academic tools are regularly being applied to the design of road race cars, but there currently no well-established benchmark cases study aerodynamics car wings in ground effect. In this paper we propose a new test case, with relatively complex geometry, supported by availability CAD model experimental results. We refer case as Imperial Front Wing, originally based on fr...