The Hadoop Distributed File System (HDFS) is designed to store very large data sets reliably, and to stream those data sets at high bandwidth to user applications. In a large cluster, thousands of servers both host directly attached storage and execute user application tasks. By distributing storage and computation across many servers, the resource can grow with demand while remaining economica...

We describe the design of Mariposa, an experimental distributed data management system that provides high performance in an environment of high data mobility and heterogeneous host capabilities. The Mariposa design unifies the approaches taken by distributed file systems and distributed databases. In addition, Mariposa provides a general, flexible platform for the development of new algorithms ...

Ischemia/reperfusion injury associated with kidney transplantation induces profound acute injury, influences early graft function, and affects long-term graft outcomes. To determine whether renal dendritic cells play any role during initial innate ischemia/reperfusion injury and the subsequent development of adaptive immune responses, we studied the behavior and function of renal graft and host...

Following entry into host cells intracellular pathogens must simultaneously evade innate host defense mechanisms and acquire energy and anabolic substrates from the nutrient-limited intracellular environment. Most of the potential intracellular nutrient sources are stored within complex macromolecules that are not immediately accessible by intracellular pathogens. To obtain nutrients for prolif...

Self-securing storage prevents intruders from undetectably tampering with or permanently deleting stored data. By keeping all versions of all data for a window of time and separating the storage system from the host operating system, self securing storage can protect its data from corruption. This paper describes a versioning file system that combines log-structuring with novel metadata journal...

As storage interconnects evolve from single-host small-scale systems, such as traditional SCSI, to the multi-host Internet-based systems of Network-attached Secure Disks (NASD), protecting the integrity of data transfers between client and storage becomes essential. However, it is also computationally expensive and can impose significant performance penalties on storage systems. This paper expl...

Emerging non-volatile memory technologies as a disk drive replacement raise some issues of software stack and interfaces, which have not been considered in disk-based storage systems. In this work, we present new cooperative schemes including software and hardware to address performance issues with deploying storage-class memory technologies as a storage device. First, we propose a new polling ...

As storage interconnects evolve from single-host small-scale systems, such as traditional SCSI, to the multi-host Internet-based systems of Network-attached Secure Disks (NASD), protecting the integrity of data transfers between client and storage becomes essential. However, it is also computationally expensive and can impose significant performance penalties on storage systems. This paper expl...