In a wide range of non-linear dynamical systems, noise may enhance the detection of weak deterministic input signals. Here, we demonstrate this phenomenon for transmembrane signaling in a hormonal model system of intracellular Ca(2+) oscillations. Adding Gaussian noise to a subthreshold extracellular pulsatile stimulus increased the sensitivity in the dose-response relation of the Ca(2+) oscill...

background: tissue injuries may provoke neuro-hormonal response which in turn may lead to release of inflammatory cytokines. we hypothesize that block of afferent sensory pathways by infiltration of 0.5% bupivacaine in the scalp may decrease neuro-hormonal response in the neurosurgical patient. methods: after obtaining informed consent, forty asa physical statuses i, ii, or iii patients between...

Objective To estimate the potential impact of using hormonal contraceptives on rates of infection with human immunodeficiency virus type 1 (HIV-1) and on pregnancy rates by theoretically removing the use of hormonal contraceptives from a study population. Methods A prospective cohort study was conducted in 3704 HIVnegative women who were enrolled in two biomedical trials that tested two vaginal...

OBJECTIVES To improve access to contraceptives in remote and rural areas, sub-Saharan African countries are allowing community health workers (CHWs) to distribute hormonal contraceptives. Before offering hormonal contraceptives, CHWs must determine pregnancy status but often lack a reliable way to do so. No studies have evaluated the impact of providing CHWs with urine pregnancy test kits. We a...

Background: Levofloxacinis a fluoroquinolone antibacterial agent with a broad spectrum of activity against different infectious disease and Gram-negative bacteria. In more than 100 countries it has therapeutic use. This study is aimed to determine Cytotoxic of Levofloxacin effects on rat testis tissue. Materials and Methods: For this experimental study, we used 50 male wistar rats which must be...

A number of excitable cell types respond to a constant hormonal stimulus with a periodic oscillation in intracellular calcium. The frequency of oscillation is often proportional to the hormonal stimulus, and one says that the stimulus is frequency encoded. Here we develop a theory of frequency encoding in excitable systems and apply it to intracellular calcium oscillations that results from inc...

INTRODUCTION: Sexual dysfunction after childbirth is reported to be prevalent worldwide. The risk factors for sexual still underexplored. Thus, this study aims determine the possible associated with among post-partum women. MATERIALS AND METHODS: This cross-sectional was conducted in nine primary care clinics Kuantan involving 420 women within six months postpartum. respondents were convenientl...

different contraceptive methods are used by breastfeeding mothers. in general, these methods are classified into two major groups, hormonal and non-hormonal. a number of studies have shown that combined oral contraceptive pills may adversely affect the quality and the quantity of human milk. in other studies it has been shown that estrogen and progesterone seem to reduce the risk of cardiac and...