In this work, a hypothesis is presented that could explain the non-homogeneous lateral distribution of membrane components in Golgi vesicles. It is shown that the non-homogeneous lateral distribution of membrane components and the specific flattened shape of Golgi vesicles are strongly coupled. In agreement with experimental evidence, it is indicated that some of the membrane components may be ...

Systems with long-range interactions can reach a Quasi Stationary State (QSS) as a result of a violent collisionless relaxation. If the system mixes well (ergodicity), the QSS can be predicted by the statistical theory of Lynden-Bell (1967) based on the Vlasov equation. When the initial distribution takes only two values, the Lynden-Bell distribution is similar to the Fermi-Dirac statistics. Su...

The initial value problem for the Vlasov-Poisson system is by now well understood in the case of an isolated system where, by definition, the distribution function of the particles as well as the gravitational potential vanish at spatial infinity. Here we start with homogeneous solutions, which have a spatially constant, non-zero mass density and which describe the mass distribution in a Newton...

Theory. We propose a novel biophysical model of the diffusion signal. Inspired by the ADC approach of [1], we consider measurements of the signal arising from a large number of individual homogeneous spin packets within a voxel. However, in contrast to the 1D model of [1], we model the 3-D Gaussian diffusion of each homogeneous spin packet with a full diffusion tensor , capturing the 3-D struct...

Chondrocytes are the living cells in articular cartilage (AC). They synthesize and maintain the extracellular matrix. Their activity is regulated by the interplay of genetic and environmental factors, such as soluble mediators, extracellular matrix composition, and mechanical factors. The mechanical environment of the chondrocytes has a significant influence on the health of the joint. In past ...

In the present paper, an asymptotic model is constructed for the short-time deformation of an articular cartilage layer modeled as transversely isotropic, transversely homogeneous (TITH) biphasic material. It is assumed that the layer thickness is relatively small compared with the characteristic size of the normal surface load applied to the upper surface of the cartilage layer, while the bott...