Objective: To analyze and compare clinico-pathologic characteristics and survival between lung tumors with mixed histologic pattern and our population of resected lung tumors with single histology in the same period. Methods: From January 1993 to December 1999, 1158 patients received resection for lung tumors. Of these, 59 (5.1%) presented a mixed histologic pattern on the surgical specimen. Th...

Nonalcoholic fatty liver disease (NAFLD), defined as abnormal accumulation (> 5%) of hepatic triglyceride without excess alcohol intake, is the most common form of chronic liver disease in adults and children in the United States. NAFLD encompasses a spectrum of histologic findings including uncomplicated steatosis, steatosis with inflammation and steatohepatitis [nonalcoholic steatohepatitis (...

BACKGROUND The histologic grade of a prostate needle-core biopsy specimen can determine whether a patient with prostate cancer is a candidate for radical prostatectomy or other treatment. Incorrect histologic grading can result in inappropriate treatment and possible liability. Thus, we conducted this study to determine the histologic-grading accuracy of prostate cancer needle-core biopsy speci...

Background Pathologic Classification of Idiopathic Pulmonary Fibrosis UIP DIP/Respiratory Bronchiolitis Interstitial Lung Disease (RBILD) AIP NSIP Clinical Features of the Idiopathic Interstitial Pneumonias UIP DIP/RBILD AIP N SIP Grading of “Cellularity” and Fibrosis Relationship of UIP and DIP Relationship of AIP and UIP Significance of NSIP—A Specific Disease or a Histologic Manifestation of...

BACKGROUND/AIM In patients with breast carcinoma there are many risk factors for assessment of breast carcinoma maturity and prognosis. Besides histological type of differentiation, cytologic criteria for the evaluation grade of the differentiation of infiltrative ductal breast carcinomas are very important for prognosis. The aim of this study was to define cytologic criteria for grading of inf...

The World Health Organization recently updated its classification of central nervous system tumors, adding 8 entities, as well as defining new variants and morphologic patterns of existing entities. Despite the continued refinement of brain tumor histologic classification and grading, there remain some diagnostic "gray zones" that challenge general surgical pathologists and neuropathologists al...

background and aims: p504s (amacr) is a mitochondrial enzyme expressed in renal cell carcinoma. some of immunohistochemical markers in renal cell tumors are independent prognostic factor and show relation with histologic grading. amacr expression increases with higher histological grading in different tumors; however, in rcc it is not obvious. in this study, we tried to investigate if any relat...