This paper describes a method of calculating the inherent visibility at all locations in a landscape (‘total viewshed’) by making use of redundant computer cycles. This approach uses a simplified viewshed program that is suitable for use within a distributed environment, in this case managed by the Condor system. Distributing the calculation in this way reduced the calculation time of our examp...

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Precision medicine promises to transform cancer treatment in the next decade through the use of high-throughput sequencing and other technologies to identify telltale molecular aberrations that reveal therapeutic vulnerabilities of each patient’s tumor [1]. This session will address the "panomics" of cancer – the complex combination of patient-specific characteristics that drive the development...

(2014). 'From the mole to the molecule': ruthenium catalyzed nitroarene reduction studied with 'bench', high-throughput and single molecule fluorescence techniques.

Advances in molecular and computational technologies have irreversibly changed the course of genetic investigation for almost all organisms. Although “single-gene” and “single investigator” studies will continue to provide detail and resolution to our understanding of biological processes, the greatest impact in this field of investigation will likely come from the high-throughput discovery too...

As interconnection networks proliferate to many new applications, a low-latency high-throughput fabric is no longer sufficient. Applications are becoming powerconstrained. In this paper, we propose an architecturallevel power model for interconnection network routers that will allow researchers and designers to easily factor in power when exploring architectural trade-offs. We applied our model...

We present a computational protocol for inference of regulatory and signaling pathways in a microbial cell, through mining “high-throughput” biological data of various types, literature search, and computer-assisted human inference. This protocol consists of four key components: (a) construction of template pathways for microbial gnomes related to the target genome, which have either been thoro...

There has been significant effort to build high throughput computing systems out of many distributed multimedia servers. These systems should accommodate a larger number of servers and should handle the ever-growing user demands. Recently, Grid computing has become one of the promising technologies that can deliver such a system. Among the many problems encountered in building Grid computing sy...

Data-intensive applications in the Condor High Throughput Computing environment can place heavy demands on network resources for checkpointing and remote data access. We have developed mechanisms to monitor, control, and schedule network usage in Condor. By managing network resources, these mechanisms provide administrative control over Condor’s network usage and improve the execution efficienc...

Motivation: Electrospray tandem mass spectrometry (ESI-MS/MS) is commonly used in high-throughput metabolomics. However, one of the key obstacles to the effective use of this technology is the difficulty in processing measured spectra to accurately and efficiently identify