The role of bile in manganese metabolism and homeostasis was studied in Holstein bull calves fed diets containing 32 ppm manganese (normal) (control) or 1,000 ppm supplemental manganese (high-manganese) for 2 weeks before and 1 week after intravenous (IV) and duodenal S4Mn dosing. After dosing, all the bile was collected at 15 and 60 minutes, hourly to 12 hr and daily to 7 days. All calves were...

Parkinson disease associated with farming and exposure to agricultural chemicals has been reported in numerous studies; little is known about Parkinson disease risk factors for those living in urban areas. The authors investigated the relation between copper, lead, or manganese emissions and Parkinson disease incidence in the urban United States, studying 29 million Medicare beneficiaries in th...

Introduction: Trace elements are important for the normal function of thyroid and prevention of its diseases. Normal activities of thyroid including the synthesis of thyroid hormones and regulation of metabolism are dependent on the presence of trace elements. On the other hand, thyroid hormones may also affect the trace element levels. In this study, we investigated the effects of induced h...

Manganese is capable of forming complex ions with many substances found naturally in the body (1). It seems reasonable to assume, therefore, that manganese injected as MnSO4 (hereafter referred to as "ionic manganese") will be complexed in the body to a varying extent shortly after administration. If the Mn is strongly chelated before it is injected, a state of competition between ligands is se...

The atomic level structure of a series of monodisperse single crystalline nanoparticles with a magnetic core of manganese ferrite was studied using X-ray absorption fine structure (EXAFS) and X-ray absorption near edge structure (XANES) techniques at both the Fe and Mn K-edges, and conventional and high resolution transmission electron microscopy (TEM and HRTEM). In particular, insights on the ...

Parkinson disease associated with farming and exposure to agricultural chemicals has been reported in numerous studies; little is known about Parkinson disease risk factors for those living in urban areas. The authors investigated the relation between copper, lead, or manganese emissions and Parkinson disease incidence in the urban United States, studying 29 million Medicare beneficiaries in th...

Studies were performed on canine cardiac Purkinje fibers to evaluate the effects of manganese on membrane electrogenesis. The results indicate that manganese has a calciumlike effect on the excitatory sodium current and inhibitory effects on potassium conductance and slow inward current. The calciumlike effect of manganese on sodium current was reflected through a leftward (toward less negative...

High-dose human exposure to manganese results in manganese accumulation in the basal ganglia and dopaminergic neuropathology. Occupational manganese neurotoxicity is most frequently linked with manganese oxide inhalation; however, exposure to other forms of manganese may lead to higher body burdens. The objective of this study was to determine tissue manganese concentrations in rhesus monkeys f...

in this work, dynamic mechanical properties of three high-manganese steels with trip/twip or fully twip characteristics are studied. high strain rate experiments in the range of true strain rates between ~500 and 1800 /s are conducted using a dynamic torsional testing setup. all the three steels show a positive strain rate sensitivity in the intermediate range of strain rates (up to 500 /s). bu...