We report the development of photoacoustic flowmetry assisted by high-intensity focused ultrasound (HIFU). This novel method employs HIFU to generate a heating impulse in the flow medium, followed by photoacoustic monitoring of the thermal decay process. Photoacoustic flowmetry in a continuous medium remains a challenge in the optical diffusive regime. Here, both the HIFU heating and photoacous...

Harmonic Motion Imaging for Focused Ultrasound (HMIFU) is a technique that can perform and monitor high-intensity focused ultrasound (HIFU) ablation. An oscillatory motion is generated at the focus of a 93-element and 4.5 MHz center frequency HIFU transducer by applying a 25 Hz amplitude-modulated signal using a function generator. A 64-element and 2.5 MHz imaging transducer with 68kPa peak pre...

BACKGROUND To evaluate the efficacy of holmium laser enucleation of the prostate (HoLEP) followed by high-intensity focused ultrasound (HIFU) for patients with huge prostate adenoma and localized prostate cancer (CaP) and compare the morbidity and efficacy results with those observed in a similar population treated only with HIFU for a follow-up period of up to 5 years. METHODS The present re...

Hypothesis: Extracorporeal high-intensity focused ultrasound (HIFU) would be used as a non-invasive local ablation for the treatment of patients with various kinds of solid tumor. Methods: A total of 1038 patients with solid tumors underwent HIFU ablation in ten Chinese hospitals. The tumors included primary and metastatic liver cancer, malignant bone tumors, breast cancer, soft tissue sarcomas...

Background: The present investigation compared the decrease in the volume of benign tumor before and after High Intensity Focused Ultrasound (HIFU) treatment to evaluate the therapeutic effects of HIFU. in terms of Lifestyle and obstetric characteristics of in patients with Benign Uterine Tumors. Materials and Methods: To collect the data on each patients’ lifestyle and obstetric characteristic...

BACKGROUND High-intensity focused ultrasound (HIFU) is a noninvasive therapy that makes entire coagulative necrosis of a tumor in deep tissue through the intact skin. There are many reports about the HIFU's efficacy in the treatment of patients with breast cancer, but randomized clinical trials are rare which emphasize on the systematic assessment of histological changes in the ablated tumor va...

To provide its therapeutic effects, High-Intensity Focused Ultrasound (HIFU) treatment makes use of ultrasonic waves that are transmitted through tissue medium. This non-invasive technology shows capacity for a variety medical applications, including tumor ablation, vascular coagulation, and gene drug delivery. Nonetheless, there many problems can arise from using this technology. The goal rese...

ing of electrical conduction across the ablation lines. With bipolar radiofrequency (RF) clamps, the PV cuff is physically clamped and burned repeatedly in order to achieve 'acute' conduction block. A question for further reflection is: are we achieving block at that moment because of local tissue trauma and inflammation resulting from simultaneous crushing and burning of the PV cuff and is tha...

BACKGROUND The aim of our multicenter study was to assess the clinical outcome and safety of ultrasound (US)-guided high-intensity focused ultrasound (HIFU) in patients with breast fibroadenoma (FA). METHODS From May 2011 to February 2013, 42 women with 51 FA in one or both breasts were selected for treatment with US-guided HIFU. Eight of 51 FA were treated twice. Patients' age ranged from 16...

In high intensity focused ultrasound (HIFU) therapy, it is important to monitor the presence and activity of microbubbles in tissue during treatment. The current methods, passive cavitation detection (PCD) and B-mode imaging have limited sensitivity, especially to small-size, non-violently-collapsing microbubbles. Here, a new method for microbubble detection is proposed, based on "twinkling" ar...