نتایج جستجو برای: hesi

تعداد نتایج: 107  

2016
John E. Doe Deborah R. Lander Nancy G. Doerrer Nina Heard Ronald N. Hines Anna B. Lowit Timothy Pastoor Richard D. Phillips Dana Sargent James H. Sherman Jennifer Young Tanir Michelle R. Embry

The HESI-coordinated RISK21 roadmap and matrix are tools that provide a transparent method to compare exposure and toxicity information and assess whether additional refinement is required to obtain the necessary precision level for a decision regarding safety. A case study of the use of a pyrethroid, "pseudomethrin," in bed netting to control malaria is presented to demonstrate the application...

2016
J. Stewart W. J. Breslin B. K. Beyer K. Chadwick L. De Schaepdrijver M. Desai B. Enright W. Foster J. Y. Hui G. J. Moffat B. Tornesi K. Van Malderen L. Wiesner C. L. Chen

The Health and Environmental Sciences Institute (HESI) Developmental and Reproductive Toxicology Technical Committee sponsored a pharmaceutical industry survey on current industry practices for contraception use during clinical trials. The objectives of the survey were to improve our understanding of the current industry practices for contraception requirements in clinical trials, the governanc...

Journal: :Birth defects research. Part B, Developmental and reproductive toxicology 2011
Bruce K Beyer Neil Chernoff Bengt R Danielsson Karen Davis-Bruno Wafa Harrouk Ronald D Hood Gemma Janer Ulla Wändel Liminga James H Kim Meredith Rocca John Rogers Anthony R Scialli

Workshops on maternal toxicity were held at the annual Society of Toxicology, Teratology Society, and European Teratology Society meetings in 2009. Speakers presented background information prior to a general discussion on this topic. The following recommendations/options are based on the outcome of the discussions at the workshops: 1. A comprehensive evaluation of all available data from gener...

2010
Syril Pettit Shelley Ann des Etages Louis Mylecraine Ronald Snyder Jennifer Fostel Robert T. Dunn Kenneth Haymes Manuel Duval James Stevens Cynthia Afshari Alison Vickers

BACKGROUND In spite of the application of toxicogenomic (TGx) data to the field of toxicology for the past 10 years, the broad implementation and full impact of TGx for chemical and drug evaluation to improve decision making within organizations and by policy makers has not been achieved. OBJECTIVES The goal of the Health and Environmental Sciences Institute (HESI) Committee on the Applicatio...

Journal: :ALTEX 2013
Louise Parks Saldutti Bruce K Beyer William Breslin Terry R Brown Robert E Chapin Sarah Campion Brian Enright Elaine Faustman Paul M D Foster Thomas Hartung William Kelce James H Kim Elizabeth G Loboa Aldert H Piersma David Seyler Katie J Turner Hanry Yu Xiaozhong Yu Jennifer C Sasaki

To address the pressing need for better in vitro testicular toxicity models, a workshop sponsored by the International Life Sciences Institute (ILSI), the Health and Environmental Science Institute (HESI), and the Johns Hopkins Center for Alternatives to Animal Testing (CAAT), was held at the Mt. Washington Conference Center in Baltimore, MD, USA on October 26-27, 2011. At this workshop, expert...

2017
Mary P Bennett Mary Bennett Lorraine Bormann Sherry Lovan Robert Cobb

Attrition can be a serious problem for nursing programs and students. Loss of students during a nursing program or through NCLEX failure is a waste of resources and results in inefficiency in the production of nurses for the workforce. Using data from 341 students admitted over a threeyear period, the goal of this study was to determine which factors best predicted student success in a Baccalau...

Journal: :The Veterinary clinics of North America. Small animal practice 1981
S P Arnoczky G B Tarvin

examination skills of the musculoskeletal system physical examination of the musculoskeletal system physical examination of the musculoskeletal system the musculoskeletal system dr. pedro schestatsky physical examination of the musculoskeletal system physical examination of musculoskeletal system socm physical exam of the musculoskeletal system pfn: sompyl0l clinical assessment of the musculosk...

Journal: :Proceedings of the Combustion Institute 2021

The oxidation of di-n-propyl-ether (DPE) was performed in a jet-stirred reactor at 1 and 10 atm, residence times 0.7 s, respectively, initial fuel concentrations 5000 1000 ppm respectively. Atmospheric pressure experiments were used for characterization cool flame products. atm experiment provided KHPs profile vs. temperature mole fraction profiles stable species which obtained through sonic pr...

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function paginate(evt) { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term pg=parseInt(evt.target.text) var data={ "year":filter_year, "term":term, "pgn":pg } filtered_res=post_and_fetch(data,url) window.scrollTo(0,0); } function update_search_meta(search_meta) { meta_place=document.getElementById("search_meta_data") term=search_meta.term active_pgn=search_meta.pgn num_res=search_meta.num_res num_pages=search_meta.num_pages year=search_meta.year meta_place.dataset.term=term meta_place.dataset.page=active_pgn meta_place.dataset.num_res=num_res meta_place.dataset.num_pages=num_pages meta_place.dataset.year=year document.getElementById("num_result_place").innerHTML=num_res if (year !== "unfilter"){ document.getElementById("year_filter_label").style="display:inline;" document.getElementById("year_filter_place").innerHTML=year }else { document.getElementById("year_filter_label").style="display:none;" document.getElementById("year_filter_place").innerHTML="" } } function update_pagination() { search_meta_place=document.getElementById('search_meta_data') num_pages=search_meta_place.dataset.num_pages; active_pgn=parseInt(search_meta_place.dataset.page); document.getElementById("pgn-ul").innerHTML=""; pgn_html=""; for (i = 1; i <= num_pages; i++){ if (i===active_pgn){ actv="active" }else {actv=""} pgn_li="
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  • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->