Background: Herpes simplex virus (HSV) encephalitis is the most common cause of sporadic encephalitis, with significant morbidity and mortality that are effectively reduced by antiviral treatment. Herpes simplex infection in pregnant women rarely results in encephalitis. The most common symptoms of a pregnant woman with herpes simplex infection are colds and skin vesicles. Herpetic encephalitis...

purpose: to present a case of herpes zoster ophthalmicus (hzo) with consequent posterior ischemic optic neuropathy (pion). case report: a 58-year-old woman with a history of hzo in her right eye which was under treatment presented with loss of vision to no light perception. on examination, positive relative afferent pupillary defect was detected; however the optic disc was normal on ophthalmosc...

  Background and Objectives: Epstein Barr Virus (EBV) is one of the members of herpesviridae family and a sub-category of Gamma herpes virinae. EBV, which normally has CR2 or CD21 receptors on B-lymphocytes, has mutagenic features for them. The virus plays an important role in causing some malignant cancers. About 30% of the cases with non-Hodgkin’s lymphoma are diffuse large B-cell l...

Herpes simplex virus type 1 was treated with 4,5'-8-trimethylpsoralen (psoralen) plus near-ultraviolet light in order to produce lesions (monoadducts and DNA cross-links) in the viral DNA. Human fibroblasts were infected by damaged virus under conditions in which either a single virus particle or several particles entered a given cell, and the fraction of virus-producing cells was determined. T...

abstract: herpes simplex encephalitis (hse) is a life threatening outcome of herpes simplex virus (hsv) infection of the central nervous system (cns). hsv accounts for 2-5 percent of all cases of encephalitis. one third of cases occur in those younger than 20 years old and one half in those older than 50 years old. clinical diagnosis is recommended in the encephalopathic, febrile patients with ...

this study was conducted to evaluate the effects of administering oral acyclovir in conjunction with topical acyclovir and steroids in the treatment of necrotizing herpetic keratouveitis. all patients with necrotizing herpetic keratouveits who have been consulted during 1996-1997 at the farbi eye hospital were studied . the patients were randomly assigned to two groups. in the first group, topi...

The synthesis of the marine natural products pyridinebetaine A and B is reported. The biological evaluation of pyridinebetaine A and B and several analogues as cytotoxic, antifungal and antiviral agents is also described. Unfortunately, none of the compounds tested showed relevant antifungal or cytotoxic activity. Only pyridinebetaine B reduced the Herpes simplex virus type 1 virus replication,...

The complete DNA sequence of herpes B virus (Cercopithecine herpesvirus 1) strain E2490, isolated from a rhesus macaque, was determined. The total genome length is 156,789 bp, with 74.5% G+C composition and overall genome organization characteristic of alphaherpesviruses. The first and last residues of the genome were defined by sequencing the cloned genomic termini. There were six origins of D...

Background and objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic proliferative disorder of unknown etiology and mainly affects young children. The histological feature is granuloma-like proliferation of langerhans-type dendritic cells. Although the possible role of viruses such as Epstein-Barr virus (EBV, Human Herpes virus -4</...