نتایج جستجو برای: hereditary nephritis
تعداد نتایج: 94751 فیلتر نتایج به سال:
the aim of this study was to investigate the possible influence of interferon-gamma (ifn- γ) gene polymorphism +874 (a/t) (rs2430561) in the susceptibility and renal complications of patients with henoch-schonlein purpura (hsp). we also studied the effects of ifn-γ allelic variation on serum levels of pro-and anti-inflammatory cytokines in hsp patients. the study population comprised 97 pa...
Alport-type familial nephritis (FN), a genetic disorder, results in progressive renal insufficiency and sensorineural hearing loss. Immunochemical and biochemical analyses of the non-collagenous (NC1) domain of type IV collagen isolated from the glomerular basement membranes (GBM) of three males with this disease demonstrate absence of the normally occurring 28-kilodalton (kD) NC1 monomers, but...
INTRODUCTION Electron microscopy (EM) has been widely utilized in the evaluation of kidney biopsies. However, few recent reports have critically assessed its diagnostic value. The aim of this study is to assess the role and value of EM in the evaluation of native kidney biopsies at our institution. MATERIALS AND METHODS A retrospective evaluation of 273 native kidney biopsies performed at our...
Background & Aims: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by various autoantibodies formation and immune complex deposition in various organs. Lupus nephritis is a common and severe manifestation of SLE that can lead to end stage renal disease and death. The aim of this study was to evaluate the long-term efficacy of cyclosporine A in the treat...
Alport's syndrome is of interest to geneticists because it has probably been the subject of more hypotheses regarding its inheritance than any other disease. The two cardinal features of hereditary nephritis and perceptive deafness were first clearly recognised by Alport in a family he reported in 1927.1 He acknowledged the help of A E Garrod and Alexander Fleming in the investigation of this f...
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