Chinese herbs nephropathy, a rapidly progressive interstitial nephropathy, has been reported in young Belgian women given a slimming regimen including Chinese herbs. It is characterized by early, severe anemia, mild tubular proteinuria, and normal arterial blood pressure. Renal histology shows an extensive, remarkably aor hypocellular interstitial fibrosis associated with tubular atrophy and gl...

Capsaicin, one of the major active components of cayenne pepper pills, is an over-the-counter substance with sympathomimetic activity used commonly by young individuals for weight loss. Here we report the case of a previously healthy young male who developed severe chest pain after using cayenne pepper pills for slimming and sustained an extensive inferior myocardial infarction. Electrocardiogr...

The obesity drug development is presently not a bright and successful story. So far, drugs reported to be effective, either from synthetic or natural sources, mostly stimulated controversy due to serious adverse effects, which ended with stopping clinical trials or even withdrawal from the market. However, obesity and its comorbidity have become rapidly a major problem in both developed and dev...

Berdasarkan data Riset Kesehatan Dasar atau Riskesdas yang dilaksanakan oleh Kementrian Republik Indonesia pada tahun 2018, diketahui bahwa angka obesitas di meningkat setiap tahunnya. Untuk mengatasi obesitas, banyak alternatif solusi tersedia, namun demikian, ada suatu metode tanpa resiko juga dapat menjadi pilihan, yakni hipnoterapi bertujuan untuk mencapai berat badan ideal, disebut sebagai...

Compared to long-chain triglycerides (LCT), medium-chain triglycerides (MCT) display some specific physico-chemical, and biological characteristics. Thus, MCT are currently used in clinical nutrition as energy-yielding substrates, and have been advocated for three decades as a useful mean for body weight reduction. This review encompasses most aspects of MCT metabolism arguing this slimming hyp...

Sibutramine, which acts as an anti-obesity drug by inhibiting reuptake of serotonin and norepinephrine, has now been banned due to cardiovascular adverse effects. However, despite being banned, it is not uncommon for people to purchase products with sibutramine or its analogues used as adulterants in non-prescription slimming products or health foods available on the internet. Sibutramine has b...

Does dietary composition in itself have any importance for weight gain and obesity? Meta-analyses of dietary intervention trials comparing ad libitum normal-fat diets with low-fat diets clearly demonstrate that a reduction in the dietary fat content decreases body fat stores (Bray & Popkin, 1998; Yu-Poth et al. 1999; Astrup et al. 2000). Energy from fat has a weaker satiating power than energy ...