نتایج جستجو برای: her2neu protein

تعداد نتایج: 1234734  

Journal: :progress in biological sciences 2013
mohammad-hadi foroughmand-araabi bahram goliaei mehdi sadeghi

prosite database contains a set of entries corresponding to protein families, which are used to identify the family of a protein from its sequence. although patterns and profiles are developed to be very selective, each may have false positive or negative hits. considering false positives as items that reduce the selectiveness of a pattern, then, the more selective pattern we have, a more accur...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز - دانشکده کشاورزی 1391

برنج یکی از غلات دانه ریز مهم در جهان است که بیش از 50% از جمعیت جهان را تغذیه می کند. عامل بیماری بلاست برنج، بیمارگر magnaporthe grisea است که یکی از مهم ترین بیماری های قارچی برنج در اغلب نواحی جهان به شمار می رود. به منظور بررسی اثر تنش قارچ بلاست بر الگوی بیان پروتئوم در کشت سوسپانسیون سلولی برنج، آزمایشی در قالب طرح کاملا تصادفی با دو رقم نعمت و طارم در دو سطح شاهد و تنش بیماری بلاست در س...

Journal: :Anticancer research 2004
Agnès J van de Wouw Rob L H Jansen Arjan W Griffioen Harry F P Hillen

BACKGROUND The unknown primary tumour (UPT) is an intriguing clinical finding in approximately 5% of all newly diagnosed patients with cancer. To evaluate a correlation between the specific immunohistochemical alterations in UPT cells and the unique clinical features of UPT patients, to define the natural history of UPT and to verify prognostic factors, we undertook a detailed clinical and immu...

Journal: :Journal of the Egyptian National Cancer Institute 2010
Sherif Adly Iman H Hewedi Nadia M Mokhtar

PURPOSE The aim of this work is to determine the possible relationship between the different profiles of molecular expression of hormone receptors and Her-2÷neu receptors to clinical and histopathological known prognostic variables for breast cancer. MATERIALS AND METHODS A total of 110 breast carcinoma tumor samples were included. In this study 4 groups or immunohistochemical profiles were d...

2011
Gema Moreno-Bueno Fernando Salvador Alberto Martín Alfredo Floristán Eva P Cuevas Vanesa Santos Amalia Montes Saleta Morales Maria Angeles Castilla Alejandro Rojo-Sebastián Alejandra Martínez David Hardisson Katalin Csiszar Francisco Portillo Héctor Peinado José Palacios Amparo Cano

Basal-like breast carcinoma is characterized by the expression of basal/myoepithelial markers, undifferentiated phenotype, highly aggressive behaviour and frequent triple negative status (ESR-, PR-, Her2neu-). We have previously shown that epithelial-mesenchymal transition (EMT) occurs in basal-like breast tumours and identified Lysyl-oxidase-like 2 (LOXL2) as an EMT player and poor prognosis m...

Journal: :Asian Pacific journal of cancer biology 2021

Objective: Gallbladder cancer (GBC) is the most common biliary tract malignancy found worldwide with very high incidence in North India especially Delhi region. It characterized by poor prognosis and ineffective treatment advanced stage. The aim of this study was to evaluate EGFR HER2/neu immunoexpression patients correlate it clinicopathological parameters so as identify GBC who can benefit fr...

2010

Lung cancer is the leading cause of cancer death in the USA. Approximately 215,020 new cases (114,690 men and 100,330 women) were diag‐ nosed and 161,840 died of lung cancer in 2008 (National Cancer Institute [NCI] 2009). The extremely high lung cancer‐related mortality, demonstrates the limited efficacy of traditional cytotoxic chemotherapy in patients with this disease [1,2]. In the past few ...

Journal: :international journal of nano dimension 0
s. imani department and research center of biology, ihu, tehran, iran. a.m. zand department and research center of biology, ihu, tehran, iran. m. saadati biotechnology research center, baqiyatallah university of medical sciences, tehran, iran. h. honnari department and research center of biology, ihu, tehran, iran. b. maddah department of chemistry, ihu, tehran, iran.

recombinant protein purification is a kind of sensitive and expensive method in genetics engineering. genetic manipulation leads to the expression of various proteins; it should be isolated with high purity finally. differed methods for protein purification are categorized, based on cast, quality, easy work and side effect of protein. in this article, we are investigating his his-tag protein pu...

Journal: :avicenna journal of medical biotechnology 0

background: in vitro simulation of developmental processes is an invaluable tool to shed light on the intrinsic mechanism of developmental biosystems such as central nervous system in mammals. chick somites have been used to simulate the neural differentiation of human neural progenitor cells. in the present study, we aimed to indicate whether somites have the ability to express required neural...

Journal: :journal of sciences, islamic republic of iran 2011
f. mansouri

a sweet water-soluble protein that reminds stable over wide ranges of temperature and ph, brazzein has various applications. its tastes like cane sugar but have no calories. however, the extraction of brazzein from its natural source is expensive and not applicable. in this study we used recombinant dna technology to provide an alternative option for cheaper mass production of brazzein. a brazz...

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