This study was made to determine the nature of tissue contributions to murine hepatic morphogenesis, the developmental potential in vitro of various hepatic regions prior to and during definitive liver development, and to accurately determine the time of onset of hepatic haematopoiesis in vitro. Embryos were precisely staged by somite counts as well as time of original mating, and tissues were ...

Objective: To correlate serum Aspartate transaminase (AST) and Platelet Ratio Index (APRI) with the degree of hepatic fibrosis in patients with non alcoholic fatty liver disease (NAFLD). Methodology: This study was conducted on patients with NAFLD presenting at Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, from July 2007 to June 2008. In all patients, platelet counts and level...

primary hepatic lymphoma (phl) is rare and possibly associated with viral hepatitis and autoimmune diseases. scleroderma could exceptionally be complicated by lymphoma. we describe phl occurring in a 52-year-old female suffering scleroderma for eight years, with no history of cytotoxic or high-dose glucocorticoid therapy. ct scan, performed to work-up abdominal discomfort, constipation, and ele...

background and objective: febrile convulsions (fc) are the most common seizure disorder in children. lumbar puncture should be considered in any case with fc who is suspected to intracranial infections. this study determined white blood cell and polymorphonuclear cell counts, and protein and glucose levels in cere-brospinal fluids (cfs) of children hospitalized with fc. methods: in this cross s...

Flaky skin (gene symbol fsn) is an autosomal recessive mutation that causes pleiotropic effects of anemia, papulosquamous skin disorder, and gastric forestomach hyperplasia. In this report, we assign fsn to distal chromosome 17 and characterize the anemia. The decrease in hematocrit levels and red blood cell counts is significant and persists throughout life in fsn/fsn mice. There is compensato...

Objective(s): Paeoniflorin (PF) has anti-oxidation, anti-inflammation, anti-apoptosis, and neuroprotection pharmacological effects against ischemic injury. The aim of the present study was to investigate the neuroprotection mechanisms of PF in cerebral ischemia-reperfusion injury rats.Materials and Methods: We established an animal model of cerebral infarct by occlusion of the middle cerebral a...

liver fibrosis is a potentially reversible response to hepatic insults, triggered by different chronic diseases most importantly viral hepatitis, alcoholic, and non-alcoholic fatty liver disease. in the course of the chronic liver disease, hepatic fibrogenesis may develop, which is attributed to various types of cells, molecules, and pathways. activated hepatic stellate cell (hsc), the primary ...