Abstract Background and Aims Neonate hyperbilirubinemia usually resolves within 3–5 days without complications however, severe neonatal jaundice (SNJ) is associated with long-term neurocognitive impairment, cerebral palsy, auditory neuropathy, deafness, or death. Globally, at least 481,000 term/near-term neonates are affected by SNJ annually, 114,000 dying an additional 63,000 surviving kernict...

Abstract Background and Aims In the field of nephrology, environmental awareness is booming we claim that it responsible for our impact. Hemodialysis treatment generates an excessive burden owing to high consumption water energy, as well production a large amount waste. On part European Kidney Health Alliance (EKHA), several proactive suggestions have been proposed worldwide. To this regard, im...

In hemodialysis, the patient’s blood is flown through an extracorporeal circuit containing a hemodialyzer. This process stimulates coagulation for several reasons, most notably the blood’s contact with the artificial surfaces of the tubing and dialyzer membrane and with air in the venous bubble trap, turbulent and stagnant blood flow, shear stress and hemoconcentration during the treatment [1]....

Abstract Background and Aims Ralstonia (RB) Burkholderia (BB) species are environmental Gram-negative bacilli responsible for several nosocomial infections in immunocompromised or frail patients. RB BB may contaminate medical devices because of their ability to survive a biofilm with low nutrient requests. Reports infection outbreaks due very few only sporadic cases, the source contamination wa...

Background:The kidney, a critical organ, is important for maintaining the bodys homeostasis system. A healthy individual excretes 1500–2000 ml of urine per 24 hours. progressive, permanent decrease kidney function known as chronic renal disease. disease staging based on declining GFR. At point when an individuals GFR under 15 ml/min, CKD taken into consideration. Dialysis frequently therap...

Abstract Background and Aims Performance hemocompatibility are the two main functions of a hemodialyzer. Synthetic dialysis membranes made from polysulfone (PSU) or polyethersulfone (PES) mainly used for treatments blended with hydrophilic agent polyvinylpyrrolidone (PVP), to improve during treatments. A novel PSU-based dialyzer (FX CorAL) an increased stabilized PVP content has been developed ...

Intravenous colistin methanesulfonate (CMS) is increasingly the last line of defense for multidrug-resistant gram-negative bacteria and is now being used as “salvage” therapy in critically ill patients (1, 7, 9, 11). CMS is converted in vivo to colistin, and these two entities have substantially different pharmacokinetics, antibacterial activities, and toxicities (7), and therefore it is import...