A new algorithm of determination of coe cients of multidimensional heat equations on the basis of temperature measurements is proposed. A system of stochastic di erential equations (SDE) can be assigned to a linear multidimensional heat equation. The solution of the heat equation can be obtained by solving the corresponding SDE by the method of statistical modeling. The sensitivity analysis is ...

The development and evaluation of a differential style heat flux gauge is presented. The sensor is constructed from spot-welded foils of copper and constantan on either side of a thin Kapton® polyimide film and is capable of measuring the heat flux and surface temperature at ten locations simultaneously. Analytical modeling was performed to estimate the sensor’s sensitivity and time response. C...

  In this study, a new method for joining aluminum tubes in subsurface structures using steel converting and aluminum welding are presented and reviewed. But near the weld area is under high thermal cycle and will cause residual stresses in heat affected zone. Therefore for assessment of proposed connection from the perspective of residual stress by using the finite element method welding of tu...

Abstract Pain is one of the most prominent symptoms of osteoarthritis. However, there is often discordance between the pain experienced by individuals with osteoarthritis and the degree of articular pathology. This suggests that individual differences, including genetic variability in the central processing of nociceptive stimuli, may impact the presentation of osteoarthritis. Here, we show tha...

The human catechol-O-methyltransferase (COMT) is a polymorphic enzyme that catalyzes the O-methylation of catechol estrogens. Recent animal studies showed that placental COMT is involved in the development of placentas and embryos, probably via the formation of 2-methoxyestradiol. In this study, we analyzed a total of 36 human term placentas to determine their cytosolic COMT activity for the O-...

Penicillin-binding proteins differ greatly in heat sensitivity and sensitivity to detergents. The partial purification of penicillin-binding 1A and 1B proteins from Escherichia coli is described.

Nitric oxide (NO) is a key signaling molecule in plants. This analysis of Arabidopsis thaliana HOT5 (sensitive to hot temperatures), which is required for thermotolerance, uncovers a role of NO in thermotolerance and plant development. HOT5 encodes S-nitrosoglutathione reductase (GSNOR), which metabolizes the NO adduct S-nitrosoglutathione. Two hot5 missense alleles and two T-DNA insertion, pro...

Temperature-sensitive transient receptor potential (TRP) ion channels are members of the large tetrameric cation channels superfamily but are considered to be uniquely sensitive to heat, which has been presumed to be due to the existence of an unidentified temperature-sensing domain. Here we report that the homologous voltage-gated potassium (Kv) channels also exhibit high temperature sensitivi...

Spontaneous baroreflex control of pulse interval (PI) was assessed in healthy volunteers under thermoneutral and heat stress conditions. Subjects rested in the supine position with their lower legs in a water bath at 34 degrees C. Heat stress was imposed by increasing the bath temperature to 44 degrees C. Arterial blood pressure (Finapres), PI (ECG), esophageal and skin temperature, and stroke ...

The role of climate sensitivity and ocean heat uptake in determining the range of climate model response is investigated in the second phase of the Coupled Model Intercomparison Project (CMIP2) AOGCM results. The fraction of equilibrium warming that is realized at any one time is less in those models with higher climate sensitivity, leading to a reduction in the temperature response range at th...