نتایج جستجو برای: heart dose

تعداد نتایج: 683169  

Objective: Diabetes is associated with vascular complications and impaired angiogenesis. Since angiogenesis plays a crucial role in vascular homeostasis in ischemic heart diseases, in this study, the effect of IMOD™ on miR-503 and CDC25 expression level which are altered in impaired angiogenesis were investigated in heart tissue of diabetic rats. Materials and Methods: Forty male Wistar rats (2...

Parviz Parvaresh Seyedeh fatemeh Khatani Zahra sadat Esmati

Introduction: Nuclear medicine techniques have been widely employed in the assessment of gastroesophageal dysfunction. Gastroesophageal reflux (GER) is a common, self-limited process in infants and children that usually resolves at 12 to 18 months of age. Clinical management of GER includes conservative treatment, thickened feedings, positional therapy and parental reassurance. On the other han...

F. Teke, H.M. Doğan, M. Gümüş, M.A. Kaya,

Background: The purpose of this study was to evaluate the characteristics of TomoDirect (TD) plans compared to conventional TomoHelical (TH) plans in chest wall irradiation in patients with breast cancer. Materials and Methods: TD and TH plans for only chest wall were retrospectively created for 30 patients previously treated with TH technique in our clinic. The beam angles were arranged to cov...

Kotteazeth Srikumar, Muthu Suriyamurthy, Muthuraman Pandurangan, Muthuviveganandavel Veerappan,

Background: Methyl 2-benzimidazole carbamate (carbendazim) is a synthetic fungicide used against organisms that cause different types of plant diseases. It is widely used as a preservative in leather, paint, textile, fruit, and paper industry. It is also used as an anticancer drug in clinical medicine. Methods: To evaluate the low dose toxicity of this compound in mammalian tissues, carbend...

2013
Markus Rey Patrick Hess Martine Clozel Stéphane Delahaye John Gatfield Oliver Nayler Beat Steiner

Ponesimod, a selective S1P1 receptor modulator, reduces the blood lymphocyte count in all tested species by preventing egress of T and B cells from thymus and peripheral lymphoid organs. In addition, ponesimod transiently affects heart rate and atrioventricular (AV) conduction in humans, effects not observed in mice, rats, and dogs with selective S1P1 receptor modulators, suggesting that the re...

Journal: :Journal of the American College of Cardiology 2000
K Swedberg C H Bergh K Dickstein J McNay M Steinberg

OBJECTIVE To evaluate the dose response relationship of moxonidine on plasma concentration of norepinephrine during acute and chronic administration in patients with congestive heart failure (CHF). BACKGROUND Sympathetic activation is increased in heart failure. Moxonidine is an imidazoline ligand acting on the central nervous system (CNS) receptors to decrease sympathetic activation. METHO...

Journal: :Radiation oncology 2016
Tawfik Giaddui Wenzhou Chen Jialu Yu Liyong Lin Charles B Simone Lulin Yuan Yutao U T Gong Q Jackie Wu Radhe Mohan Xiaodong Zhang Jaques B Bluett Michael Gillin Kevin Moore Elizabeth O'Meara Jennifer Presley Jeffrey D Bradley Zhongxing Liao James Galvin Ying Xiao

BACKGROUND To establish the feasibility of the dosimetric compliance criteria of the RTOG 1308 trial through testing against Intensity Modulation Radiation Therapy (IMRT) and Passive Scattering Proton Therapy (PSPT) plans. METHODS Twenty-six lung IMRT and 26 proton PSPT plans were included in the study. Dose Volume Histograms (DVHs) for targets and normal structures were analyzed. The quality...

2017
Marciana Nona Duma Anne-Claire Herr Kai Joachim Borm Klaus Rüdiger Trott Michael Molls Markus Oechsner Stephanie Elisabeth Combs

BACKGROUND AND PURPOSE The aim of the present study was to evaluate if it is feasible for experienced radiation oncologists to visually sort out patients with a large dose to the heart. This would facilitate large retrospective data evaluations. And in case of an insufficient visual assessment, to define which structures should be contoured and which structures can be skipped as their dose can ...

Journal: :iranian journal of pharmaceutical research 0
mitra korani deparment of pharmacology, faculty of medicine, tehran university of medical sciences, tehran, iran. seyed mehdi rezayat 1- deparment of pharmacology, faculty of medicine, tehran university of medical sciences, tehran, iran. 2- depatment of nanotechnology, faculty of advanced sciences and technology in medicine, tehran university of medical sciences, tehran, iran, 3- department of toxicology and pharmacology, pharmaceutical sciences branch, islamic azad university, tehran, iran. sepideh arbabi bidgoli department of toxicology and pharmacology, pharmaceutical sciences branch, islamic azad university, tehran, iran.

silver nanoparticles (ag nps) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. present study compares the tissue levels of ag nps in different organs of guiana pigs quantitatively after dermal application and analysis the morphological changes and pathological abnormalities on the basis of the ag nps tissue levels. before toxicological assessments,the ...

Journal: :British journal of anaesthesia 1981
E Major A J Verniquet T K Waddell T M Savege D E Hoffler W Aveling

Three doses (1.5, 2.0 and 2.5 mg kg-1) of diisopropyl phenol (ICI 35 868) were compared for induction and maintenance of anaesthesia in healthy females undergoing short gynaecological procedures. Induction of anaesthesia was smooth and rapid. Cardiovascular changes (which were dose-dependent) included a decrease in arterial pressure and an increase in heart rate. These changes were magnitudes c...

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