Traumatic brain and spinal cord injuries are severe burdens for the patients, their relatives, the health care providers and society as a whole. Recent data demonstrate the magnitude of the problem: It is mostly a disease of the young gen-eration (age 20-45 years) with mortality rates for severe traumatic brain injury (TBI) between 40-50%. In approximately 60% of cases, multiple trauma is accom...

The incidence of traumatic brain injury (TBI) among military personnel is at its highest point in U.S. history. Experimental animal models of blast have provided a wealth of insight into blast injury. The mechanisms of neurotrauma caused by blast, however, are still under debate. Specifically, it is unclear whether the blast shockwave in the absence of head motion is sufficient to induce brain ...

296 long-term consequences, including those related to blast-induced traumatic brain injuries (TBIs), shows an increasing trend. The Defense and Veterans Brain Injury Center (DVBIC) estimated, on the basis of medical records and actual medical diagnoses, that more than 202,000 service members were diagnosed with TBI between 2001 and 2010, with the overwhelming distribution of mild TBI caused by...

traumatic brain injury is a leading cause of death in developed countries. it is estimated that only in the united states about 100,000 people die annually in parallel among the survivors there is a significant number of people with disabilities with significant costs for the health system. it has been determined that after moderate and severe traumatic injury, brain parenchyma is affected by m...