OBJECTIVE Cannabis is associated with psychotic outcomes in numerous studies, an effect that is commonly attributed to Δ (9)-tetrahydrocannabinol (Δ 9-THC). An increasing number of authors identify cannabidiol, another component of the cannabis plant, as an antipsychotic agent. The objective of the current study is to investigate the role of cannabidiol content in the association between cannab...

The recent findings that Delta9tetrahydrocannabinol (Delta9THC), the active agent in marijuana and hashish, (1) is self-administered intravenously, (2) potentiates the rewarding effects of electrical brain stimulation, and (3) can establish conditioned place preferences in laboratory animals, suggest that these drugs activate biologically primitive brain reward mechanisms. Here, we identify two...

Gas chromatography was used to study the cannabinoid content ("potency") of illicit cannabis seized by police in England in 2004/5. Of the four hundred and fifty two samples, indoor-grown unpollinated female cannabis ("sinsemilla") was the most frequent form, followed by resin (hashish) and imported outdoor-grown herbal cannabis (marijuana). The content of the psychoactive cannabinoid delta 9-t...

Supported in part by Grant MH 03030, National Institute of Mental Health. Marihuana smoking or hashish ingestion has long been reported to increase hunger and appetite. "Marihuana hunger" was described as coming on for 3 to 6 hours following the drug, with a special craving for sweets.' Another modern investigation' found that subjects did not experience hunger during the first 3 hours despite ...

The cannabis plant (Cannabis sativa L.) and products thereof (such as marijuana, hashish and hash oil) have a long history of use both as a medicinal agent and intoxicant. Over the last few years there have been an active debate regarding the medicinal aspects of cannabis. Currently cannabis products are classified as Schedule I drugs under the Drug Enforcement Administration (DEA) Controlled S...

Data from the European School Survey Project on Alcohol and other Drugs have shown that adolescent substance use is a growing problem in western and particularly Eastern European countries. This paper describes the development, implementation and results of the Icelandic Model of Adolescent Substance Use Prevention. The Icelandic Model is a theoretically grounded, evidence-based approach to com...

HASHISH is a fascinating subject. It is not so very long since we still thought that there might be an important future for it in medicine, but opinions about it have varied between extremes. Some have regarded it as a panacea, while others think it is purely a poison; but of course this is also true of attitudes to alcohol! Comparatively recently, we have had editorials in the Lancet (1963) te...

Notes, jottings and writings smuggled out of a British prison have been fused into this book, or as it is better described by Timothy Leary; this 'whispered manuscript'. One of the authors, Brian Barritt, was sentenced to 'four years' meditation' for attempting to bring four pounds of hashish through H.M. Customs in 1966, and on his release from prison, with the help of David Ball, he put the s...

Abstract Despite the social, health, law enforcement, and economic importance of illegal drug supply, lack information understanding regarding these supply chains stands out. This paper carries out a disaggregated analysis structure hashish chain from Morocco to Europe explain value contributions at each level, end-price formation, management practices. The methodology adopted is based on mixed...