Objective (s): Silicate bioceramics containing Zn and Ca like hardystonite (Hr) with chemical formula Ca2ZnSi2O7 has attracted the attention of researchers in biomedical field due to its remarkable biological and mechanical properties. The new generation of bioceramics can applied in bone tissue engineering to substitute with infected bone. However, these zirconium-silicate bioceramics have pro...

the aim of this study was to evaluate the effect of long-term reduced tillage on yield and weeds of spring barley. treatments consisted of three tillage systems including: (a) conventional tillage (ct), (b) reduced tillage (rt), and (c) herbicide tillage (ht) as the main plot, and two cultivars of spring barley (tocada and rastik) as subplots. the results showed that the yield of both cultivars...

Objective(s): The purpose of this study was to investigate cytotoxicity and membrane toxicity effects induced by Mesobuthus eupeus venom (MEV) on the HT-29 cell line. Materials and Methods: To determine the in vitro cytotoxicity via MTT assays, HT-29 (as cancer cell line) and Hek-293T (as normal cell) were treated through different conce...

Serotonin [5-hydroxytryptamine (5-HT)] released from mast cells or platelets in peripheral tissues is one of the important inflammatory mediators in pain and hyperalgesia. The involvement of 5-HT in pain is complex because it could inhibit or facilitate nociceptive transmission, reflecting the presence of multiple 5-HT subtype receptors on peripheral and central nociceptors. The present study a...

Within the family of serotonin receptors, the 5-hydroxytryptamine-3 (5-HT(3)) receptor is the only ligand-gated ion channel. It is composed of five subunits, of which the 5-HT(3A) and 5-HT(3B) subunits are best characterized. Several studies, however, have reported on the functional diversity of native 5-HT(3) receptors, which cannot solely be explained on the basis of the 5-HT(3A) and 5-HT(3B)...

Serotonin (5-hydroxytryptamine; 5-HT) plays key roles in sleep-wakefulness regulation. Evidence indicates that 5-HT2 receptors are involved mainly in non-rapid eye movement sleep (NREMS) regulation and respiratory control. Here, we investigated the relative contribution of 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor subtypes to NREMS and breathing during sleep, using 5-HT2 subtype-selective ligan...

Abstract We present and analyse the Hough transform (HT) to recognise approximate space curves in digital models, a problem that is not currently addressed by standard HT. Our method works on meshes point clouds applies models even incomplete or affected noise, thus being suitable for analysis of deriving from 3D scans. In our approach we take advantage recent HT formulation algebraic define bo...

Hashimoto's thyroiditis (HT) may affect the epidemiology, pathogenesis, diagnosis, clinical course and prognosis of differentiated thyroid cancers (DTC).In this study, our aim is to increase awareness in these cases by revealing different aspects DTCs found with HT compared only DTCs. For purpose, current studies HT+DTC were reviewed, compared, evaluated, their differences from DTC revealed. It...

The aim of the current study was to identify enteric 5-HT(4) splice variants, locate enteric 5-HT(4) receptors, determine the relationship, if any, of the 5-HT(4) receptor to 5-HT(1P) activity, and to ascertain the function of 5-HT(4) receptors in enteric neurophysiology. 5-HT(4a), 5-HT(4b), 5-HT(4e), and 5-HT(4f) isoforms were found in mouse brain and gut. The ratio of 5-HT(4) expression to th...

Widespread adoption of high-temperature polymer electrolyte membrane fuel cells (HT-PEMFCs) and HT-PEM electrochemical hydrogen pumps (HT-PEM ECHPs) requires models computational tools that provide accurate scale-up optimization. Knowledge-based modeling has limitations as it is time consuming information about the system not always available (e.g., material properties interfacial behavior betw...