BACKGROUND Many patients with limited disease (LD) behave similarly to those with extensive disease (ED) from a prognostic point of view. On the other hand, a proportion of patients with ED small-cell lung cancer (SCLC) behave similarly to those with LD. PATIENTS AND METHODS In this retrospective study analysis, 764 patients with proven SCLC were included and managed with the same therapeutic...

conclusions stress had a moderate level in dental students of study, which requires more attention. due to the most level of stress in students of fifth and sixth years, it is recommended to take specific actions for this sensitive period of dentistry education. background studying dentistry environment is important to assess stress causes, which is harmful for educational system. objectives th...

PURPOSE To compare sleep quality of overweight versus normal weight women in the second and third trimesters of pregnancy. METHODS A cross-sectional study involving 223 women with 14 or more weeks of pregnancy, 105 of them overweight (pre-pregnancy body mass index - BMI - ≥25.0 kg/m2) and 118 of normal weight (BMI 18.5-24.9 kg/m2), attending the prenatal care clinic. The Brazilian version of ...

materials and methods: 32 new zealand rabbits were randomly divided into three groups: control group, high-cholesterol group and losartan group. the level of weights, serum lipid levels and inflammatory factors, such as il-6 and hs c-reactive protein were detected before the losartan intervention and two months after the losartan intervention respectively. the content of angii was detected on l...

The aim of the study was to examine the drug resistance analysis of gefitinib-targeted therapy in non-small cell lung cancer (NSCLC). In total, 156 NSCLC patients without surgical treatment were selected, including 117 cases of adenocarcinoma (75%), to receive single gefitinib 0.25 g/day or combined with platinum chemotherapy. Computed tomography was used to evaluate tumor growth for the respon...

PURPOSE This study was designed to evaluate the efficacy of medical treatment of Peyronie's disease. MATERIALS AND METHODS A total of 109 patients with Peyronie's disease who had been treated from January 2011 to December 2014 were retrospectively reviewed in this study. Forty-four patients (Group 1) were treated with 12 mg of potassium para-aminobenzoate daily. Sixty-five patients (Group 2) ...

This study aimed at determining the choice and administration duration of ideal antibiotic prophylaxis before percutaneous nephrolithotomy (PNL) operation, a treatment modality for nephrolithiasis. The study included 90 patients who had no internal problem, yet had a negative urine culture and underwent a PNL operation. We compared infection rates between ciprofloxacin and ceftriaxone groups an...

Objective: To preliminarily assess the immune status of patients with prostate cancer through detecting various immune indexs and then analyse the relationship between immune status and clinical factors such as clinical stage, pathological classification and endocrine therapy. Methods: Flow cytometry was used to detect the percentage of CD4, CD8and NK cells in peripheral blood lymphocyte (PBL) ...

OBJECTIVE To determine the prevalence, severity and pattern of early childhood caries (ECC) in Moshi Municipality, Tanzania. DESIGN Cross-sectional study. SETTING Moshi Municipality, Kilimanjaro region, Tanzania. SUBJECTS Three hundred and seventy two randomly selected children aged three to five years (157 males and 215 females) in 2008. RESULTS Overall caries prevalence was 30.1% with...

Background: The present study aims to examine the pharmacotherapy effects of citicoline in patients suffering traumatic brain injury with DAI and GCS less than or equal to 8 diagnosis. The treatment efficacy of citicoline was assessed by the malondialdehyde (MDA) levels in plasma as a marker of oxidative stress and GCS clinical assessment of patients. Furthermore, because of the relation betwee...