Ubiquitination & Sumoylation C e l l C y c l e & D N A T r a n s a c t i o n s In eukaryotes, the several meters long genomic DNA needs to be packed into chromosomes with a diameter of only several hundred micrometers. This is achieved through an elaborated scheme of packaging that starts with the formation of nucleosomes from DNA winding around an octamer core of histones H2A/H2B/H3/H4, foll...