OBJECTIVE To compare the immediate effect of xylitol chewing gum and xylitol mouth rinse on mutans streptococci (MS) levels in the saliva of adults with systemic sclerosis (SSc). METHODS Thirteen female adults with SSc were assigned randomly to either the xylitol chewing gum or xylitol mouth rinse groups. Participants in the chewing gum group were given 2 pellets (2.12g) of commercial xylitol...

An attempt has been made to formulate new chewing gum device for ondansetron hydrochloride in the form of tablet. The new drug delivery system was obtained, at room temperature, by direct compression using conventional pharmaceutical equipment. The resulting chewing gum tablets comprise a gum core combined with fillers, antioxidants, coloring agent and plasticizers, which provide smooth appeara...

BACKGROUND Flavor perception, the integration of taste and odor, is a critical factor in eating behavior. It remains unclear how such sensory signals influence the human brain systems that execute the eating behavior. METHODS WE TESTED CEREBRAL BLOOD FLOW (CBF) IN THE FRONTAL LOBES BILATERALLY WHILE SUBJECTS CHEWED THREE TYPES OF GUM WITH DIFFERENT COMBINATIONS OF TASTE AND ODOR: no taste/no ...

The current series of experiments investigated the effects of the timing of gum chewing on cognitive function, by administering a battery of cognitive tasks to participants who chewed gum either prior to or throughout testing, and comparing their performance to that of controls who did not chew gum. Chewing gum was associated with performance advantages on multiple measures when gum was chewed ...

Chewing gum allergy is a rare condition in emergency settings. A 48-year-old man presented to the emergency department with generalised itchiness which was more prominent on the periorbital areas, nausea, vomiting, and dyspnoea after taking chewing gum. Vital signs showed hypotension with a blood pressure of 72/45 mmHg, and heart rate 95 beats per minute. Auscultation of the chest revealed diff...

Postoperative gastrointestinal dysfunction remains a source of morbidity and the major determinant of length of stay after abdominal operation. There are many different reasons for postoperative gastrointestinal dysfunction such as stress response, perioperative interventions, bowel manipulation and so on. The mechanism of enhanced recovery from postoperative gastrointestinal dysfunction with t...

Background & aim: Cesarean section (CS) accounts for 35% of all surgical operations in Iran. Post cesarean ileus is a complication of CS. There are various pharmaceutical and non-pharmaceutical ways for the treatment of this condition. Given the fact that the non-pharmaceutical approaches are better tolerated and often inexpensive, the present study was conducted to evaluate the effect of chewi...

BACKGROUND Enhanced recovery, in part, aims to reduce postoperative gastrointestinal dysfunction (PGID). Acquired - or established- vagal dysfunction may contribute to PGID, even for surgery not involving the gastrointestinal tract. However, direct evidence for this is lacking. We hypothesized that chewing gum reduces morbidity (including PGID) by preserving efferent vagal neural activity posto...

BACKGROUND The goal of this prospective study was to estimate the absorbed (radiation) doses to salivary glands in radioiodine therapy of thyroid cancer under chewing-gum stimulation using (124)I positron emission tomography (PET)/computed tomography (CT) imaging. METHODS Duplex ultrasonography was conducted in three test persons for visual comparison of the glandular blood flow with three di...