Here, we present the first instance of Guillain-Barre syndrome variant in a patient with beta thalassemia and iron overload who had a history of transfusion before the onset of symptoms. Our patient was a 50- year-old Persian woman with history of intermediate thalassemia who had been treated with pack cells because of low hemoglobin level. Ten days after transfusion, she developed numbness of ...

BACKGROUND Diseases that cause acute flaccid paralysis (AFP) often progress rapidly, thus may cause life threatening complications, therefore, their diagnosis and cure are important. This study was carried out to investigate the causes of acute generalized weakness in children referred to Amirkola Children's Hospital, in Babol, Iran. METHODS In this case series, the epidemiological causes of ...

The author reports a case of recurrent Guillain-Barre syndrome with a period of nearly complete remission during 2 years between acute episodes. The case is reported because of its rarity.

introduction:guillain-barre syndrome(gbs) is the most common cause of acute flaccid paralysis. respiratory failure is the most serious short-term complication of gbs and invasive mechanical ventilation is required in 30% of patients.moreover,60% of those who are intubated develop major complications including pnemonia,sepsis,gi bleeding and pulmonary embolism. thus respiratory failure predictio...

thymoma is the most common neoplasm of anterior mediastinum with incidence peaks during the fourth, fifth and sixth decades of life. two-thirds of patients are asymptomatic and identified accidentally by chest x-rays . of the total, 40-70 % of patients have one or more parathymic syndromes of which myasthenia gravis (mg) is the most common and reported in 10-50% . gullain-barre syndrome (gbs) h...

background: diseases that cause acute flaccid paralysis (afp) often progress rapidly, thus may cause life threatening complications, therefore, their diagnosis and cure are important. this study was carried out to investigate the causes of acute generalized weakness in children referred to amirkola children’s hospital, in babol, iran. methods: in this case series, the epidemiological causes of ...

Background and Objectives: Guillain-Barre´ Syndrome (GBS) is an acute-onset, monophasic, immune-mediated polyneuropathy that often follows an antecedent infection. Special nutritional support has an important role in these patients. Methods: A 6 years old girl with GBS was admitted to PICU of Dr. Sheikh Children Hospital (Mashhad, Iran). Chief compliance for hospitalization was inability to w...

There are two main hypotheses concerning the aetiology of the Guillain-Barre syndrome. First, that it is a primary virus infection, and, secondly, that it is a form of 'neuro-allergy' (Furtado, 1950) with the allergic state resulting from either an antecedent illness (usually a virus disease) or an immunizing injection. The terms 'acute infectious polyneuritis' and 'acute post-infective polyneu...

With the reduction of poliomyelitis Guillain Barre Syndrome has become the most common cause of acute flaccid paralysis in both developed and developing countries with an incidence 0.9-1.1 cases per 100000 children below 15 years of age [1,2]. A common misconception is that the GBS has a good prognosisbut up to 20% of patients remain severely disabled and approximately 5% die, despite immunothe...

Treating Central Nervous System (CNS) neuro-inflammational disorders is of great importance. A key aspect of this treatment includes regulation of Cell-Mediated and humoral immune systems. Previous treatment mostly consisted of systemic immunosuppressive drugs. In addition to having adverse side effects, these drugs were also inefficient, such as methotrexate- Cyclophosphamide-Azathioprine. Rec...