Iodine preparations for external use are recommended for treating pressure ulcers with manifestations of infection and necrosis. These ulcers abundantly produce wound exudates, which could be absorbed by water-soluble base. In this study we aimed to improve the previously reported methodologies for water absorption and new methodologies were developed in Franz diffusion cell with 100kDa molecul...

Sixty patients were treated with either acyclovir 2% ointment or idoxuridine 1% ointment 5 times a day in a stratified randomised double-blind clinical trial. The 2 antiviral agents were equally effective.

background persian oak (quercus brantii) belongs to the fagaceae family. it is a medicinal plant which is commonly used by the tribes in south western iran to treat inflammatory and gastric ulcers. objectives the aim of this study was to evaluate the effectiveness of persian oak ointment on dermal wound healing in rats. materials and methods for making full-thickness wounds in rats, the excisio...

background wound healing is a dynamic process with inflammatory response and oxidative reaction in the damaged area. alpha ointment (ao) and arnebia euchroma (arnebia) are herbal medicines with antioxidant and anti-inflammatory effects that can be used as wound healing agents. ao is a commonly used ointment while arnebia is a newly introduced one. objectives we aimed to compare the effects of a...

The in vitro and in vivo antimicrobial evaluation of the formulated ointment of alkaloidal extract of Enantia chlorantha Oliv. (Annonaceae) was the concern of this study. The alkaloidal fraction of the stem bark extract was formulated into simple ointment using British Pharmacopoeia formula for preparation of simple ointment. Agar diffusion and agar dilution methods were used for the in vitro a...

BACKGROUND An aerosol foam formulation of fixed combination calcipotriol 50 μg/g (Cal) and betamethasone 0.5 mg/g (as dipropionate; BD) has been developed for psoriasis vulgaris treatment. OBJECTIVE To compare Cal/BD aerosol foam pharmacodynamic activity with Cal/BD ointment and with other topical corticosteroids of different potencies by assessing vasoconstrictor potential. METHODS A Phase...

The benefits of vitamin D derivatives for the treatment of chronic plaque psoriasis are well documented. Of importance is how compatible they are with, and how they compare to, other established treatments for psoriasis. This paper reviews 15 studies with calcitriol 3 μg g(-1) ointment (Silkis(®)/Vectical(™) ointment; Galderma Laboratories) applied twice daily for up to 52 weeks. The ointment w...

BACKGROUND AND OBJECTIVE In 1972, Dumas and Scholtz developed the psoriasis plaque test to evaluate the potency of local corticosteroids. Through further modification of this method, the efficacy between antipsoriatic products can be differentiated. This method allowed for the simultaneous application of several products to different test sites in the same psoriasis patient. The objective of th...

Panchavalkala is one of the ideal combinations for a vast range of therapeutics focused in Ayurveda like Vranaropana, Shothahara, Graahi, Visarpahara, etc. Researchers in recent and past evaluated anthelmintic, antimicrobial, wound healing etc. activities of these plants in combination and individual too. Panchavalkal is widely used in different form like Kwath, powder, ointment and Malahara et...