Rates of tumor cell loss, replication, and growth were determined simultaneously for P-815 mastocytoma cells placed in culture or transplanted as a peritoneal ascites tumor. Cytokinetic parameters were concordant in vitro to in vivo for P-815 cells growing in the presence of syngeneic DBA/2 resident or proteose peptone-elicited macrophages and under allogeneic C57BL/6 nonimmune conditions. Unde...

INTRODUCTION Kawasaki disease is an acute, self-limiting childhood systemic vasculitis with unknown etiology. Because there is no diagnostic test for Kawasaki disease, the diagnosis is based on clinical criteria. An important clinical sign that is not included in the classical clinical criteria for Kawasaki disease is a reaction at the Bacille Calmette-Guérin inoculation site that are present i...

2. Jouanguy E, Altare F, Lamhamedi S, Revy P, Emilie J-F, Levin M, et al. Interferonγ–receptor deficiency in an infant with fatal bacille Calmette-Guérin infection. N Engl J Med. 1996;26:1956–60. 3. Casanova JL, Blanche S, Emile JF, Jouanguy E, Lamhamedi S, Altare S, et al. Idiopathic disseminated bacillus CalmetteGuérin infection: a French national retrospective study. Pediatrics. 1996;98:774–...

According to Seneca, the ability excel beyond one’s destiny in any circumstance makes one noble. One of those who succeeded without fail was Jacques Guérin, a chemist made major contribution creation and subsequent codification myth carefully moulded around most important figures modern culture, Marcel Proust. Although relics Proust’s life oeuvre, that trained industrialist Guérin preserved, ar...

Background: Bacillus Calmette-Guérin (BCG) vaccination is recommended for newborn infants worldwide to prevent tuberculosis. However, complications do occur inevitably in a very low rate, among which the most serious is disseminated disease. The disseminated bacillus Calmette–Guérin disease is a rare disease with high fatality, and can be seen among persons with an underlying immunodeficiency. ...

Signaling by extracellular nucleotides through P2 purinergic receptors affects diverse macrophage functions; however, its role in regulating antimicrobial radicals during bacterial infection has not been investigated. Mycobacterium tuberculosis-infected macrophages released ATP in a dose-dependent manner, which correlated with nitrite accumulation. P2 receptor inhibitors, including oxidized ATP...

essentials of respiratory care, 4th edition. St. Louis:Mosby Elsevier; 2005:103. 13. L’Her E, Roy A. Bench tests of simple, handy ventilators for pandemics: performance, autonomy, and ergonomy. Respir Care 2011;56(6):751-760. 14. Lyazidi A, Thille AW, Carteaux G, Galia F, Brochard L, Richard JC. Bench test evaluation of volume delivered by modern ICU ventilators during volume-controlled ventila...

Complete deficiency of either of the two human interferon (IFN)-gamma receptor components, the ligand-binding IFN-gammaR1 chain and the signaling IFN-gammaR2 chain, is invariably associated with early-onset infection caused by bacille Calmette-Guérin vaccines and/or environmental nontuberculous mycobacteria, poor granuloma formation, and a fatal outcome in childhood. Partial IFN-gammaR1 deficie...

I read with interest the article on prone ventilation in acute respiratory distress syndrome (ARDS) by GUÉRIN [1] in the European Respiratory Review. In this extensive review, the author elaborated on the rationale, evidence and limitations of the application of prone position in ARDS patients. It is understood that excellent research has been conducted on the topic of prone position ventilatio...