نتایج جستجو برای: gsk3b
تعداد نتایج: 241 فیلتر نتایج به سال:
Genes in the Wnt (wingless)/ β -catenin signaling pathway have been implicated in schizophrenia pathogenesis. No study has examined this pathway in the broader context of psychosis symptom severity. We investigated the association between symptom severity scores and expression of 25 Wnt pathway genes in blood from 19 psychotic patients. Significant correlations between negative symptom scores a...
Suxiao Jiuxin Pill (SX), a traditional Chinese medicine compound consisting primarily of tetramethylpyrazine and borneol, has been reported to protect against ischemic heart disease. However, the effects of SX on mitochondrial injury and gene expression in various signaling pathways are unclear. The aim of the present study was to investigate the effects of SX on mitochondrial injury and to scr...
Numerous patientswithosteosarcoma either are not sensitive to chemotherapyor developdrug resistance to current chemotherapy regimens. Therefore, it is necessary to develop several potentially useful therapeutic agents. Dihydromyricetin is the major flavonoid component derived from Ampelopsis grossedentata, which has a long history of use in food and medicine. The present study examined the anti...
The article recently published in the journal Cancer Prevention Research entitled, "Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma" (1), highlights a potentially useful drug for the treatment of neuroblastoma. Didymin appears to inhibit neuroblastoma growth in vivo and in vitro, induces apoptosis, and reduces vimentin expression, a marker of epithelial-tome...
Microvascular and macrovascular complications associated with type 2 diabetes are leading causes of morbidity and mortality. In fact, cardiovascular (CV) complications account for a major portion of health care costs in patients with diabetes. Although lifestyle changes and pharmacotherapy aimed at CV disease risk factor modification are the mainstay of medical treatment, revascularization (sur...
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