The aetiology of breast cancer is multifactorial. While there are known genetic predispositions to the disease it is probable that environmental factors are also involved. Recent research has demonstrated a regionally specific distribution of aluminium in breast tissue mastectomies while other work has suggested mechanisms whereby breast tissue aluminium might contribute towards the aetiology o...

Ethanol consumption affects maternal nutrition, the mothers' antioxidant balance and the future health of their progeny. Selenium (Se) is a trace element cofactor of the enzyme glutathione peroxidase (GPx). We will study the effect of ethanol on Se bioavailability in dams and in their progeny. We have used three experimental groups of dams: control, chronic ethanol and pair-fed; and three group...

The United States Environmental Protection Agency (EPA) requires the determination of important trace elements in a variety of environmental samples. Graphite furnace atomic absorption methods are recommended for some elements including As, Se, Cd, Pb, Tl, Sb, Ag, Be and Cr. Graphite furnace analyses can be difficult due to chemical and spectral interferences. Quantification in atomic absorptio...

カ ド ミウム(Cd)作 業者 のCd曝 露 指 標 として,血 液 お よび 尿 中Cdの 測 定 が有 効 であ り1),こ れ ら生体 試 料 中 のCd測 定方 法 と しては黒 鉛 炉原 子 吸 光法2~6)が 広 く 用 い られ て い る.こ の方 法 に よるCd定 量 では, Cdお よび そ の化合 物 の融点 が低 いた め,原 子 化 段階 以 前 での 揮 散 が問 題 で あ り,対 策 と して適 当な 干渉 抑制 剤 を添 加 す る ことに よ り,揮 散 を 抑制 す る方 法 が と られ て い る. Cd定 量 に 対 して は, HNO32-4), NH4H2PO43,4), NH4NO33-5), NH4F4,6)お よびPd(NO3)25)な どが 干渉 抑制 剤 と して提 唱 され て い る.血 中Cd(Cd-B)の 定量 に従...

Now that the level of concern for a toxic blood lead concentration is 0.482 mumol/L (10 micrograms/dL), laboratories must meet new requirements to shorten analysis times and increase accuracy and precision of blood lead determinations. We used a matrix-matching method to estimate the lead concentration in blood by graphite furnace atomic absorption spectroscopy (GFAAS). For CDC proficiency samp...

The solid-phase extraction (SPE) method for the preconcentration of trace amounts of cadmium using synthetic zeolite A-4 and its determination by graphite furnace atomic absorption spectrometry (GFAAS) was investigated. The preconcentration conditions, such as the optimum pH range of the sample solution for the adsorption of cadmium and the kind of acid solution for dissolving the cadmium-adsor...