Intermittent hypoxia (IH) is associated with increased endothelial dysfunction and cardiovascular disorders. Exosomes released in biological fluids may act as vehicles for propagating such damage, modifying the functional phenotype of endothelial cells. Drug interventions, however, may provide protection for the endothelium, in spite of exosomal activity. Using an experimental human model of IH...

We present an extension to common realtime toon/cel-shading rendering techniques for treating reflective and transparent surfaces in a 3D toon-shading environment. Our approach takes advantage of multi texturing hardware and simple fragment and vertex shader programs. This allows a broad usage on todays gaming platforms.

Hydroxyapatite (HAp) is often used as a bone-implant material because it is biocompatible and osteoconductive. However, HAp possesses poor rheological properties and it is inactive against disease-causing microbes. To improve these properties, we developed a green method to synthesize multifunctional composites containing: (1) cellulose (CEL) to impart mechanical strength; (2) chitosan (CS) to ...

Network activity in the lateral central amygdala (CeL) plays a crucial role in fear learning and emotional processing. However, the local circuits of the CeL are not fully understood and have only recently begun to be explored in detail. Here, we characterized the intrinsic circuits in the CeL using paired whole-call patch-clamp recordings, immunohistochemistry, and optogenetics in C57BL/6J wil...

We developed a simple and one-step method to prepare biocompatible composites from cellulose (CEL) and chitosan (CS). [BMIm(+)Cl(-)], an ionic liquid (IL), was used as a green solvent to dissolve and prepare the [CEL+CS] composites. Since majority (>88%) of IL used was recovered for reuse by distilling the aqueous washings of [CEL+CS], the method is recyclable. XRD, FTIR, NIR, (13)C CP-MAS-NMR ...

Malaria transmission is dependent upon many hydrology-driven ecological factors that directly affect the vectorial competence, including the presence of suitable habitats for the development of anopheline larvae. Larval habitats were identified and characterized at three malaria endemic villages (Ban Khun Huay, Ban Pa Dae, and Ban Tham Seau) in Mae Sot district, Tak Province, in northwestern Th...

BACKGROUND Patients with chronic kidney disease (CKD) are at high risk of cardiovascular disease (CVD). Endothelial progenitor cell (EPCs) dysfunction plays a key role in this pathogenesis. Uremic retention toxins have been reported to be in associated with EPC dysfunction. Advanced glycation end-products (AGEs) free adducts, including nepsilon-(carboxymethyl)lysine (CML) and nepsilon-(carboxye...

BACKGROUND The detection of unknown mutations is important in research and medicine. For this purpose, a mismatch-specific endonuclease CEL I from celery has been established as a useful tool in high throughput projects. Previously, CEL I-like activities were described only in a variety of plants and could not be expressed in an active form in bacteria. RESULTS We describe expression of activ...

Chronic eosinophilic leukaemia (CEL) is a rare myeloproliferative disorder of unknown etiology characterized by an autonomous, clonal proliferation of eosinophilic precursors resulting in persistently increased number of eosinophils in the peripheral blood and bone marrow. There is vaguely overlapping clinico – pathological picture of CEL with idiopathic hypereosinophilic syndrome (HES) which o...

Purified non-starch polysaccharides (NSP) affect intestinal nutrient flow and hence microbial fermentation in pigs. Therefore, we investigated the effect of NSP differing in viscosity and fermentability on colonic fermentation and bacterial populations in eight ileal-cannulated barrows (BW 30 kg) fed a cornstarch-casein based diet supplemented with 5% low fermentable , low viscous cel lulose (C...