ANATOMY CONNECTIVE TISSUE Connective tissue has two components: cells and intra-cellular matrix.(20) The cells in unspecialized connective tissue consist of fibroblasts, macrophages, plasma cells, mast cells, fat cells, and pigment cells. Fibroblasts, which are concerned with the production of the intracellular matrix, are the most numerous. They are very active during wound repair and multiply...

Cleome viscosa L. (Cleomaceae) is an important traditional medicine of the Indian-Ayurvedic and Chinese-medicine system documented for rheumatic arthritis, hypertension, malaria, neurasthenia, and wound healing. The plant is also known as Asian spider flower and is distributed throughout the greater part of India. The present study explored the wound healing property of C. viscosa methanol extr...

The present study aimed to investigate the potential involvement of specific T-cell subpopulations in granulation tissue formation in chronic suppurative otitis media (CSOM). Fifteen patients with CSOM were enrolled in this study. Granulation tissues were obtained from the middle ear cavity. Hematoxylin and eosin staining was performed for histopathological observation, and different T-cell sub...

CONTRACTING GRANULATION TISSUES CONTAIN FIBROBLASTS THAT DEVELOP CHARACTERISTICS TYPICAL OF SMOOTH MUSCLE: (a) They contain an extensive cytoplasmic fibrillar system. (b) They show immunofluorescent labeling of their cytoplasm with human anti-smooth muscle serum. (c) The nuclei show complicated folds and indentations, indicative of cellular contraction. (d) There are cell-to-cell and cell-to-st...

The commonly practiced removal of granulation tissue during periodontal surgery, aiming to eliminate infection and optimize healing conditions, may also remove progenitor stem cells that could otherwise support periodontal regeneration. The present study aimed to investigate if cells with embryonic stem cell properties are present in periodontal granulation tissue. During the course of flap sur...

Granulation tissue is a transitional replacement for normal dermis, which eventually matures into a scar during the remodelling phase of healing. It is characterised from unwounded dermis by its extremely dense network of blood vessels and capillaries, elevated cellular density of fibroblasts and macrophages and randomly organised collagen fibres (Ovington and Schultz, 2004). Healthy granulatio...