OBJECTIVES To characterize human immunodeficiency virus (HIV)-associated granuloma annulare (GA) by clinical, microscopic, and molecular methods and to investigate the role of Epstein-Barr virus infection in the pathogenesis of GA. DESIGN Patients were evaluated clinically, and biopsy specimens of lesional skin were examined by light microscopy. Polymerase chain reaction and in situ hybridiza...

A biopsy from the lesion on the hand was consistent with features of localized granuloma annulare. The patient was reassured that the condition was self-limited. The lesion on her calf, however, grew larger and new nummular and annular plaques developed that ultimately involved her legs, arms, abdomen, and back. A new diagnosis was made of generalized granuloma annulare. During the next 21⁄2 ye...

Subcutaneous granuloma annulare (SGA) is a benign inflammatory disorder that may be alarming in its presentation because of its rapid growth and extensive differential diagnosis. The purpose of our study was to improve the appropriate evaluation and management of pediatric patients with subcutaneous scalp nodules. This article presents the clinical presentation, histopathologic data, evaluation...

A 55 year old female came to Skin OPD with extensive pruritic annular papules and plaques over both upper limbs, lower limbs, back and abdomen. Biopsy from one of the lesion confirmed histopathologiclly Granuloma annulare. This case is being presented for its extensive skin involvement without any systemic disorder.

Both clinical and pathologic findings must be considered when diagnosing figurate skin lesions, which are often seen in routine practice. Although a skin biopsy may sometimes be diagnostic, more often the information provided is nonspecific. In an attempt to offer an approach to diagnosing these dermatoses, we have classified annular lesions according to the presence of lymphocytic, neutrophili...

Perforating granuloma annulare (GA) is a rare subset of GA with an unknown etiology and chronic course. Herein, we report the case of 72 year-old women with a 3-month history of a post-traumatic, persistent, erythematous and exudative plaque located on her left leg. Differential diagnosis included mycobacterial infection, subcutaneous mycosis, perforating dermatoses, pyoderma and squamous cell ...