Procalcitonin (PCT) and C-reactive protein serve as biomarkers of infection in patients with sepsis/bacteremia. The present study assessed the clinical characteristics of 280 patients with suspected sepsis who were admitted to Tohoku Medical and Pharmaceutical University Hospital between January 2012 and December 2013. Among the patients, 133 and 147 were positive and negative for PCT, respecti...

INTRODUCTION Intensive care mortality of HIV-positive patients has progressively decreased. However, critically ill HIV-positive patients with sepsis present a worse prognosis. To better understand this condition, we propose a study comparing clinical, etiological and inflammatory data, and the hospital course of HIV-positive and HIV-negative patients with severe sepsis or septic shock. METHO...

Epidemiology and surveillance of neonatal sepsis helps in implementation of rational empirical antibiotic strategy. The present study was conducted to record the frequency of bacterial isolates of neonatal sepsis and their sensitivity pattern in neonates treated in our tertiary care NICU. In this retrospective study, neonates in whom neonatal sepsis was suspected and blood culture done were inc...

Sepsis caused by Gram-positive bacterial pathogens is a major fatal disease but its molecular basis remains elusive. Toll-like receptor 2 (TLR2) has been implicated in the orchestration of inflammation and sepsis but its role appears to vary for different pathogen species and clones. Accordingly, Staphylococcus aureus clinical isolates differ substantially in their capacity to activate TLR2. He...

Neonatal sepsis is a common cause of neonatal morbidity and mortality in developing countries. It is a serious bacterial infection of blood with a clinical syndrome characterized by systemic signs of infection and bacteremia in the first month of life. Factors associated with positive blood culture and perinatal deaths among neonates are rarely described in developing countries. This study aime...

aims: the internal unit and icu of hospitals are a suitable environment for growing of bacteria such as staphylococcus epidermidis and pseudomonas, acinetobacter. the aim of our study was to evaluate the effect of different disinfectants on bacteria isolated from the surface of hospitals in isfahan. instrument & methods: in this study, 200 samples were randomly selected from different parts of ...

BACKGROUND Health care databases are a valuable resource for infectious disease epidemiology if diagnoses are accurately coded. We examined the ability of diagnostic coding to accurately identify Gram-negative bacteremia. METHODS We randomly selected 100 patients among 1,703 patients recorded in the Danish National Patient Register with a diagnosis of either "septicemia/sepsis due to other Gr...