background: the role of the hospital environment as a source of dissemination of pathogens is critical. environmental surfaces in the intensive care units (icus) are suitable for the growth of gram-negative bacteria that normally circulate between the environment and patients and can cause outbreaks of nosocomial infections. in this study, the prevalence of gram-negative bacilli in the environm...

Background: Isolation of common pathogens involved in ocular infection and their in-vitro susceptibility to commonly used ocular antibiotics, as well as the trends in antibiotic resistance developed by these pathogens were investigated. Material/Methods: All patients with suspected bacterial ocular infections presenting between march 2010 and feb 2011 were examined under slit lamp microscope an...

background :   imipenem-resistant gram negative bacteria, resulting from metallo-beta-lactamase (mbls)-producing strains have been reported to be among the important causes of nosocomial infections and of serious therapeutic problem worldwide. because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all beta-lactams....

background and objectives: patients at intensive-care-unit (icu) are at risk of acquiring nosocomial infections which contributes to higher rates. approximately 25% of all hospital infections and 90% of outbreaks occur in icus. multi-resistant gram-negative rods are important pathogens in icus, causing high rate of mortality. the purpose of this study was to investigate the antimicrobial resist...

Background and Objective: Owing to the new patterns of antibiotic resistance, selection of the appropriate antibiotics for the treatment of nosocomial infections, especially gram-negative bacilli, has become a big challenge. Therefore, the aim of this study was to evaluate the antibiotic resistance of nosocomial infections with Gram-negative bacilli in Iran during the years 2012-2014. Material...

Studies in mammals uncovered important signaling roles of nitric oxide (NO), and contributions to innate immunity. Suggestions of conservation led us to explore the involvement of NO in Drosophila innate immunity. Inhibition of nitric oxide synthase (NOS) increased larval sensitivity to gram-negative bacterial infection, and abrogated induction of the antimicrobial peptide Diptericin. NOS was u...