A novel, convenient and efficient three-component reaction for synthesizing substituted pyrroles from primary amines and electron deficient acetylenic compounds in the presence of ammonium thiocyanate in water leads to the formation of pyrroles in good yields.

Eggshell was found to be a versatile heterogeneous catalyst for the synthesis of pyrano[3,2-c]quinoline derivatives in good yields. This protocol has the advantages of environmental friendliness, short reaction time, low cost and convenient operation.

1,1’-(Ethane-1,2-diyl)dipyridinium bistribromide (EDPBT) was used as a chemoselective and effective organocatalyst for the silylation of hydroxyl groups as well as desilylation of trimethylsilyl ethers under mild conditions at room temperature with good to excellent yields.

1,1’-(Ethane-1,2-diyl)dipyridinium bistribromide (EDPBT) was used as a chemoselective and effective organocatalyst for the silylation of hydroxyl groups as well as desilylation of trimethylsilyl ethers under mild conditions at room temperature with good to excellent yields.

Tetrahydropyranylation of alcohols and phenols, acetylation of aldehydes and N-Boc protection of amines are efficiently catalyzed by melamine trisulfonic acid (MTSA). All reactions were performed at room temperature in good to high yields.

The reaction of stoichiometric amounts of dialkyl acetylenedicarboxylates with alkyl isocyanides and 5,5-diaryl thiohydantoins in toluene and catalytic amount of p-TSA afforded imidazo[2,1-b][1,3]thiazines in good overall yields

The adducts produced in the reaction between trialkyl phosphites and acetylenic esters were trapped by hydantoins to produce highly functionalized dialkyl 2-(2,5-dioxo-4,4-diphenylimidazolidin-1-yl) succinate in good yields.

One pot solvent less synthesis of amidoalkylnaphthol derivatives via reaction of aldehydes, 2-naphthol and acetamide/urea in the presence of phenylphosphinic acid is  described. This methodology provides a simple synthetic route to amidoalkylnaphthols in good to high yields.   

The reactive intermediate generated by the addition of tert-butyl and 1,1,3,3-tetramethyl butyl isocyanide and cyclohexyl isocyanide to dialkyl acetylenedicarboxylate was trapped by 3-hydroxy pyridine to produce highly functionalized 4H-chromenes in fairly good  yields

A novel, convenient and efficient multi-component reaction for synthesis of phosphonate derivatives from activated acetylenic compounds with 2-hydroxyacetophenone in the presence of phosphites in water lead to the formation of phosphonates in good yields.