Glycoprotein gp52 exists within the mature human cytomegalovirus (HCMV) envelope in heterodimeric, disulphide-linked complexes with glycoproteins gp95 and gp130. Biochemical studies involving immunoprecipitations and Western blots have demonstrated that gp52 is the glycoprotein B (gB) homologue of HCMV but that gp95 and gp130 are probably separate gene products. The distribution of this putativ...

The potential of gold nanoparticles (AuNPs) in therapeutic and diagnostic cancer applications is becoming increasingly recognized, which focuses on their efficient and specific delivery from passive accumulation in tumour tissue to directly targeting tumor-specific biomarkers. AuNPs functionalized by pH low insertion peptide (pHLIP) have recently revealed the capability of targeting acidic tiss...

A common use of crowd sourcing is to obtain labels for a dataset. Several algorithms have been proposed to identify uninformative members of the crowd so that their labels can be disregarded and the cost of paying them avoided. One common motivation of these algorithms is to try and do without any initial set of trusted labeled data. We analyse this class of algorithms as mechanisms in a game-t...

Gold nanoparticles (GNPs) protected by poly(2-ethyl-2-oxazoline) (POZ) of different molecular weights (Mw = 5, 50, 200 and 500 kDa) were synthesised characterised dynamic light scattering, nanoparticle tracking analysis, zeta potential measurement transmission electron microscopy. It was established that the use POZ with 50 kDa resulted in formation GNPs low polydispersity while greater led to ...

The tripeptide glutathione is a major antioxidant and redox buffer with multiple roles in plant metabolism. Glutathione biosynthesis is restricted to the cytosol and the plastids and the product is distributed to the various organelles by unknown mechanisms. In the present study immunogold cytochemistry based on anti-glutathione antisera and transmission electron microscopy was used to determin...

In computational models of argumentation, argument justification has attracted more attention than statement justification, and significant sensitivity losses are identifiable when dealing with the justification of statements by otherwise appealing formalisms. This paper reappraises statement justification as a formalism-independent component in argument-based reasoning. We introduce a novel ge...