OBJECTIVE Zinc is essential for many biochemical processes and also for cell proliferation. Thyroid hormones influence zinc metabolism by affecting zinc absorption and excretion. Additionally, zinc deficiency affects thyroid function. The aim of the present study was to evaluate a possible association of zinc levels with thyroid volume, thyroid hormones and thyroid autoantibody levels in health...

A controlled prospective study of autoantibody profile on black Kenyan patients with non-toxic goitre (116), thyrotoxicosis (131) and age, sex matched hospital controls is reported. The prevalence of thyroid microsomal and thyroglobulin antibodies is 3.5% in smooth non-toxic goitre and is 5.2% in the nodular non-toxic goitre compared to 1% of the control. The results reflect that autoimmune thy...

the thyroid gland is diseased?atrophied in myxoedema, and (usually) hypertrophied in exophthalmic goitre?and inasmuch as both diseases affect women much more frequently than men. But in their mode of development and the character of many of their symptoms the two diseases are very different. The symptoms of myxoedema are almost always developed in a very slow, insidious, and gradual manner ;x t...

BACKGROUND & OBJECTIVE In post salt iodization phase endemic goitre and associated iodine deficiency disorders (IDD) were found prevalent in a randomly selected rural area of Sundarban delta and its adjoining areas of West Bengal. The present investigation was thus undertaken to study the total goitre rate, urinary iodine and thiocyanate excretion pattern of the school going children, iodine co...

Non-toxic goitre is endemic in Greece (Malamos Koutras, Kostamis, Kralios, Rigopoulos, and Zerefos, I966a), and detailed biochemical studies have implicated iodine deficiency as the main causative factor (Malamos, Miras, Koutras, Kostamis, Binopoulos, Mantzos, Levis, Rigopoulos, Zerefos, and Tassopoulos, I966b). However, in the endemic regions studied, both goitrous and non-goitrous persons are...

In 2000, India revoked the ban on production and sale of non-iodised salt. We conducted a study in the north 24 Parganas district in the state of West Bengal to assess the prevalence of goitre, status of urinary iodine excretion (UIE) level and to estimate iodine content of salts at the household level. We surveyed 363 school children aged eight to ten years selected using a multistage cluster ...

Dean, colleagues, I am very honoured by your invitation to give the Duncan lecture for 1997. In speaking of Dr Duncan’s legacy in a remote New Guinea valley, I would like to focus on the contribution made by research in cerebral palsy that has been carried out in Papua New Guinea and in Liverpool, dividing Duncan’s legacy into three time periods: Past—up to 1979; Present—1979 to 1997 and Future...