Chlamydiae are prokaryotic, gram negative, intracellular parasites, causing a number of human diseases with serious sequelae. The exact mechanism of chlamydial attachment and entry into the host cell is still unclear. Chlamydia trachomatis, SA2F (L2) was tested for the activity of glycosidases. Glycosidases are involved in the synthesis and breakdown of cell-wall polysaccharides, and have a piv...

A total of 16 marine strains belonging to the genus Arenibacter, recovered from diverse microbial communities associated with various marine habitats and collected from different locations, were evaluated in degradation of natural polysaccharides and chromogenic glycosides. Most strains were affiliated with five recognized species, and some presented three new species within the genus Arenibact...

It has been previously shown that dextran sulfate administered to diabetic rats accumulates in the liver and kidney, and this could be due to a malfunction of the lysosomal digestive pathway. The aim of the present study was to evaluate the expression and activities of lysosomal enzymes that act upon proteins and sulfated polysaccharides in the livers of diabetic rats. Diabetes mellitus was ind...

Novel carbasugars derived from cyclohexane-1,2-dicarboxylic acid were synthesized and tested for inhibitory activity towards fungal glycosidases from Aspergillus oryzae and Penicillium canescens. Significant inhibition was observed, which magnitude depended on configuration of substituents.

The effect of either high-cellulose (15%) or regular-cellulose (5%) diets on fecal bacterial glycosidases was assessed in two groups of ten Wistar rats, each given an injection of 1,2-dimethylhydrazone, and in two groups of six control rats. During a 4-month period, fecal activities of bacterial beta-galactosidase and beta-acetylglucosaminidase were reduced markedly in control rats maintained o...