نتایج جستجو برای: glucose regulated protein 78kda

تعداد نتایج: 1471106  

2012
Daisuke Morito Kazuhiro Nagata

Over the past two decades, heat shock proteins (HSPs) have been implicated in inflammatory responses and autoimmunity. HSPs were originally believed to maintain protein quality control in the cytosol. However, they also exist extracellularly and appear to act as inflammatory factors. Recently, a growing body of evidence suggested that the other class of stress proteins such as, endoplasmic reti...

Journal: :iranian journal of veterinary research 2013
r. m. nandre sh. fatima g. bhupal h. j. derashri c. g. joshi

the indian riverine buffaloes are more susceptible to variations in the environment. these variations affect seminal plasma proteins, which in turn affect fertility. this study was conducted to evaluate variations in the indian bubalus bubalis seminal plasma protein profile using two-dimensional polyacrylamide gel electrophoresis (2d-page) during winter and summer seasons, and its relation with...

Journal: :The Journal of biological chemistry 2002
Tsuyoshi Hirota Toshiyuki Okano Koichi Kokame Hiroko Shirotani-Ikejima Toshiyuki Miyata Yoshitaka Fukada

In mammals, peripheral circadian clocks are present in most tissues, but little is known about how these clocks are synchronized with the ambient 24-h cycles. By using rat-1 fibroblasts, a model cell system of the peripheral clock, we found that an exchange of the culture medium triggered circadian gene expression that was preceded by slow down-regulation of Per1 and Per2 mRNA levels. This prof...

C. G. Joshi, G. Bhupal H. J. Derashri R. M. Nandre Sh. Fatima

 The Indian riverine buffaloes are more susceptible to variations in the environment. These variations affect seminal plasma proteins, which in turn affect fertility. This study was conducted to evaluate variations in the Indian Bubalus bubalis seminal plasma protein profile using two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) during winter and summer seasons, and its relation wit...

2011
Susana B. Bravo Jorge E. Caminos Carmen R. González María J. Vázquez María F. Garcés Libia A. Cepeda María E. R. García-Rendueles Antonio Iglesias-Gamarra Consuelo Gómez-Díaz Miguel Lopez Justo P. Castaño Carlos Diéguez Rubén Nogueiras

The stomach secretes a wide range of peptides with essential metabolic functions, and thereby plays an important role in the regulation of energy homeostasis. Disulfide isomerase glucose-regulated protein 58 (GRp58) is a molecular chaperone member of the endoplasmic reticulum (ER) stress signaling pathway, which is a marker for human gastric cancer. Since GRp58 seems to be regulated by a phosph...

Journal: :PLoS ONE 2009
Kamille Smidt Niels Jessen Andreas Brønden Petersen Agnete Larsen Nils Magnusson Johanne Bruun Jeppesen Meredin Stoltenberg Janetta G. Culvenor Andrew Tsatsanis Birgitte Brock Ole Schmitz Lise Wogensen Ashley I. Bush Jørgen Rungby

BACKGROUND Ion transporters of the Slc30A- (ZnT-) family regulate zinc fluxes into sub-cellular compartments. beta-cells depend on zinc for both insulin crystallization and regulation of cell mass. METHODOLOGY/PRINCIPAL FINDINGS This study examined: the effect of glucose and zinc chelation on ZnT gene and protein levels and apoptosis in beta-cells and pancreatic islets, the effects of ZnT-3 k...

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