نتایج جستجو برای: gleason grading
تعداد نتایج: 22073 فیلتر نتایج به سال:
Expert’s summary: After the international WHO sponsored consensus meeting in Stockholm 2004, ‘‘International Consultation on Predictors of Patient Outcome in Prostate Cancer’’ [1,2], the International Society of Urological Pathology (ISUP) identified a need for an additional analysis of the Gleason system with a greater representation from the urological pathology community. More than 70 intern...
Gleason grading of prostatic specimens remains as one of the most powerful factors predicting prognosis in patients with prostate cancer. This grading system was created by Donald Gleason about 49 years ago and it takes into account the 2 most prevalent grades in the tumor sample, but it does not consider the presence of a third high grade pattern when it represents less than 5% of the whole ra...
A modified Gleason grading system as proposed in the 2005 International Society of Urological Pathology (ISUP) consensus meeting is the current grading system for prostate cancer. With this modified ISUP Gleason grading system, many Gleason score (GS) 6 cancers by the old grading system are upgraded to GS7 cancers on biopsy diagnosis even with minimal quantity (≤5%) of Gleason pattern 4 (GP4) c...
PURPOSE Gleason grading is an important predictor of prostate cancer (PCa) outcomes. Studies using surrogate PCa end points suggest outcomes for Gleason score (GS) 7 cancers vary according to the predominance of pattern 4. These studies have influenced clinical practice, but it is unclear if rates of PCa mortality differ for 3 + 4 and 4 + 3 tumors. Using PCa mortality as the primary end point, ...
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