SCANNING AND TRANSLUCENT ELECTRON MICROSCOPIC OBSERVATION OF SQUAMO-GLANDULAR JUNCTION IN THE ESOPHAGO-GASTRIC JUNCTION Yoshio OKADA*t, Yasusada AKAMINE, Kazuo KARASAWA and Kinya SAWADA * 2nd Surgical Department (if Aichi Cancer Center Hospital t Department rif Thoracic Surgery, Chest Disease Research Institute, Kyoto University Squamo-glandular junction in the esophago-gastric junction was obs...

Glandular trichomes are metabolic cell factories with the capacity to produce large quantities of secondary metabolites. Little is known about the connection between central carbon metabolism and metabolic productivity for secondary metabolites in glandular trichomes. To address this gap in our knowledge, we performed comparative metabolomics, transcriptomics, proteomics, and 13C-labeling of ty...

OBJECTIVES The aims of this study were to assess the number of cases diagnosed as glandular neoplasia (national report code 6) of cervical (6A) and non-cervical (6B) types on ThinPrep (TP) and SurePath (SP) liquid-based cytology (LBC) samples and to calculate the positive predictive value (PPV) of these diagnoses for significant glandular and/or squamous pathology for local audit and as a contr...

OBJECTIVE Salivary gland secretion is dependent on cholinergic stimulation via autonomic nerves and calcium signalling in acinar cells. Secretory dysfunction associated with SS may be partly caused by the damaging effects of increased glandular concentrations of nitric oxide (NO) derived from up-regulation of inducible NO synthase (iNOS) that accompanies glandular inflammation. The present stud...

The incidence of glandular cervical malignancy is steadily increasing. Glandular abnormalities are more frequently diagnosed on cervical smears. In this study, we attempt to evaluate our experience with glandular cytology and to assess the sensitivity and specificity of the ThinPrep (TP) over conventional Papanicolaou (Pap) smears. Glandular abnormalities during a 3-yr period from October 2000 ...

The pathogenesis of endocervical glandular lesions are not clearly understood. The aims of this study are to evaluate the etiologic role of human papillomavirus (HPV) 16/18 and the relationship of HPV 16/18, p53 and MIB-1 expressions in endocervical glandular dysplasia (EGD), adenocarcinoma in situ (AIS) and adenocarcinoma. The materials included 14 endocervical adenocarcinoma and 5 AIS and 18 ...

OBJECTIVE This study was undertaken to assess baseline endometrial molecular events in the ATAC (Arimidex, tamoxifen, alone, or in combination) trial of breast cancer adjuvant therapy. STUDY DESIGN Estrogen receptor (ER) and progesterone receptor (PR) levels and markers of cell proliferation (Ki67) and apoptosis ( Bcl -2) were assessed in 93 patients at baseline. RESULTS An inactive/atrophi...